90
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      MicroRNA and Transcription Factor: Key Players in Plant Regulatory Network

      review-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Recent achievements in plant microRNA (miRNA), a large class of small and non-coding RNAs, are very exciting. A wide array of techniques involving forward genetic, molecular cloning, bioinformatic analysis, and the latest technology, deep sequencing have greatly advanced miRNA discovery. A tiny miRNA sequence has the ability to target single/multiple mRNA targets. Most of the miRNA targets are transcription factors (TFs) which have paramount importance in regulating the plant growth and development. Various families of TFs, which have regulated a range of regulatory networks, may assist plants to grow under normal and stress environmental conditions. This present review focuses on the regulatory relationships between miRNAs and different families of TFs like; NF-Y, MYB, AP2, TCP, WRKY, NAC, GRF, and SPL. For instance NF-Y play important role during drought tolerance and flower development, MYB are involved in signal transduction and biosynthesis of secondary metabolites, AP2 regulate the floral development and nodule formation, TCP direct leaf development and growth hormones signaling. WRKY have known roles in multiple stress tolerances, NAC regulate lateral root formation, GRF are involved in root growth, flower, and seed development, and SPL regulate plant transition from juvenile to adult. We also studied the relation between miRNAs and TFs by consolidating the research findings from different plant species which will help plant scientists in understanding the mechanism of action and interaction between these regulators in the plant growth and development under normal and stress environmental conditions.

          Related collections

          Most cited references178

          • Record: found
          • Abstract: found
          • Article: not found

          Abiotic stress, the field environment and stress combination.

          Farmers and breeders have long known that often it is the simultaneous occurrence of several abiotic stresses, rather than a particular stress condition, that is most lethal to crops. Surprisingly, the co-occurrence of different stresses is rarely addressed by molecular biologists that study plant acclimation. Recent studies have revealed that the response of plants to a combination of two different abiotic stresses is unique and cannot be directly extrapolated from the response of plants to each of the different stresses applied individually. Tolerance to a combination of different stress conditions, particularly those that mimic the field environment, should be the focus of future research programs aimed at developing transgenic crops and plants with enhanced tolerance to naturally occurring environmental conditions.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Origin, biogenesis, and activity of plant microRNAs.

            MicroRNAs (miRNAs) are key posttranscriptional regulators of eukaryotic gene expression. Plants use highly conserved as well as more recently evolved, species-specific miRNAs to control a vast array of biological processes. This Review discusses current advances in our understanding of the origin, biogenesis, and mode of action of plant miRNAs and draws comparisons with their metazoan counterparts.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              A microRNA as a translational repressor of APETALA2 in Arabidopsis flower development.

              X. Chen (2004)
              Plant microRNAs (miRNAs) show a high degree of sequence complementarity to, and are believed to guide the cleavage of, their target messenger RNAs. Here, I show that miRNA172, which can base-pair with the messenger RNA of a floral homeotic gene, APETALA2, regulates APETALA2 expression primarily through translational inhibition. Elevated miRNA172 accumulation results in floral organ identity defects similar to those in loss-of-function apetala2 mutants. Elevated levels of mutant APETALA2 RNA with disrupted miRNA172 base pairing, but not wild-type APETALA2 RNA, result in elevated levels of APETALA2 protein and severe floral patterning defects. Therefore, miRNA172 likely acts in cell-fate specification as a translational repressor of APETALA2 in Arabidopsis flower development.
                Bookmark

                Author and article information

                Contributors
                Journal
                Front Plant Sci
                Front Plant Sci
                Front. Plant Sci.
                Frontiers in Plant Science
                Frontiers Media S.A.
                1664-462X
                12 April 2017
                2017
                : 8
                : 565
                Affiliations
                [1] 1School of Biosciences and Biotechnology, Faculty of Science and Technology, National University of Malaysia, Selangor Malaysia
                [2] 2Department of Plant Breeding and Genetics, University College of Agriculture and Environmental Sciences, The Islamia University of Bahawalpur, Punjab Pakistan
                [3] 3Centre of Plant Biotechnology, Institute of Systems Biology, National University of Malaysia, Selangor Malaysia
                [4] 4Department of Chemistry, Faculty of Mathematics and Natural Sciences, Syiah Kuala University, Darussalam, Banda Aceh Indonesia
                Author notes

                Edited by: Agnieszka Ludwików,Adam Mickiewicz University in Poznań, Poland

                Reviewed by: Agnieszka Kiełbowicz-Matuk, Polish Academy of Sciences (PAN), Poland; Sailendra Nath Sarkar, University of Calcutta, India

                *Correspondence: Ismanizan Ismail, maniz@ 123456ukm.edu.my

                This article was submitted to Plant Biotechnology, a section of the journal Frontiers in Plant Science

                Article
                10.3389/fpls.2017.00565
                5388764
                28446918
                aed68a28-0c3c-4952-b753-197981efd3a2
                Copyright © 2017 Samad, Sajad, Nazaruddin, Fauzi, Murad, Zainal and Ismail.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 13 January 2017
                : 29 March 2017
                Page count
                Figures: 2, Tables: 3, Equations: 0, References: 236, Pages: 18, Words: 0
                Funding
                Funded by: Universiti Kebangsaan Malaysia 10.13039/501100004515
                Award ID: DIP-2015-018
                Funded by: MyBrain15 scholarship: Ministry of Higher Education, Malaysia 10.13039/501100003093
                Categories
                Plant Science
                Review

                Plant science & Botany
                mirnas,transcription factors,plant development,stress response,plant regulators

                Comments

                Comment on this article