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      Recovery from COVID-19 Pneumonia in a Patient with Acute Severe Colitis

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          Abstract

          Introduction

          The coronavirus disease 2019 (COVID-19) pandemic has increased concern regarding SARS-CoV-2 infection in inflammatory bowel disease (IBD) patients, especially those on immunosuppressive therapies or with active disease. There are limited reports describing the clinical features of COVID-19 in an IBD population, and the impact of immunosuppression on the severity of the infection remains unclear.

          Case Report

          A 33-year-old female patient with a long history of ulcerative colitis, poorly controlled, was admitted with COVID-19 a few days after being discharged from the hospital for treatment of acute severe ulcerative colitis. High-risk factors for COVID-19 complications, i.e., high-dose steroids (40 mg prednisone) and severe active disease, were present at admission. Despite the development of extensive pulmonary involvement, the patient had a favorable outcome.

          Discussion

          Management of IBD patients during the COVID-19 pandemic has been challenging. Measures to minimize the potential risk of SARS-CoV-2 infection, including strict social distancing and self-isolation, in the IBD population have been recommended, especially for high-risk patients. Although steroid tapering and persistence of biologics are advised by professional groups, the best treatment strategy for IBD patients presenting a flare during the outbreak has yet to be defined.

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          Most cited references 3

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          Management of IBD during the COVID-19 outbreak: resetting clinical priorities

          The coronavirus disease (COVID-19) worldwide outbreak has led to a dramatic challenge for all healthcare systems, including inflammatory bowel disease (IBD) centres. Here, we describe the fast changes and clinical issues that IBD specialists could face during this SARS-CoV-2 infection pandemic, highlighting the potential rearrangements of care and resetting of clinical priorities.
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            A fatal case of COVID-19 pneumonia occurring in a patient with severe acute ulcerative colitis

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              Relevant Infections in Inflammatory Bowel Disease, and Their Relationship With Immunosuppressive Therapy and Their Effects on Disease Mortality

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                Author and article information

                Journal
                Inflamm Intest Dis
                Inflamm Intest Dis
                IID
                Inflammatory Intestinal Diseases
                S. Karger AG (Allschwilerstrasse 10, P.O. Box · Postfach · Case postale, CH–4009, Basel, Switzerland · Schweiz · Suisse, Phone: +41 61 306 11 11, Fax: +41 61 306 12 34, karger@karger.com )
                2296-9403
                2296-9365
                June 2020
                6 May 2020
                6 May 2020
                : 5
                : 2
                : 93-97
                Affiliations
                aDivision of Gastroenterology and Hepatology, Department of Gastroenterology, Hospital das Clínicas, School of Medicine, University of São Paulo, São Paulo, Brazil
                bDepartment of Gastroenterology, Hospital das Clínicas, School of Medicine, University of São Paulo, São Paulo, Brazil
                cInstituto da Criança e do Adolescente, Hospital das Clínicas, School of Medicine, University of São Paulo, São Paulo, Brazil
                dLaboratory of Clinical and Experimental Gastroenterology (LIM-07), Hospital das Clínicas, School of Medicine, University of São Paulo, São Paulo, Brazil
                Author notes
                *Karoline Soares Garcia, Division of Gastroenterology and Hepatology, Department of Gastroenterology, Hospital das Clínicas, School of Medicine, University of São Paulo, 255, Doutor Enéas de Carvalho Aguiar Ave., São Paulo, SP 05403000 (Brazil), karolinesoaresg@ 123456gmail.com
                Article
                iid-0005-0093
                10.1159/000508161
                7493790
                Copyright © 2020 by S. Karger AG, Basel
                Page count
                Figures: 3, References: 19, Pages: 5
                Categories
                Case Report

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