0
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Breast cancer treatment and sulfotransferase.

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Sustained exposure to excessive estrogen is an established risk factor for breast cancer. Sulfotransferase (SULT)-mediated sulfonation represents an effective approach for estrogen deprivation as estrogen sulfates do not bind and activate estrogen receptors (ERs). The nuclear receptor (NR) superfamily functions as a sensor for xenobiotics as well as endogenous molecules, which can regulate the expression of SULT.

          Related collections

          Author and article information

          Journal
          Expert Opin Ther Targets
          Expert opinion on therapeutic targets
          Informa Healthcare
          1744-7631
          1472-8222
          Jun 2015
          : 19
          : 6
          Affiliations
          [1 ] Institute of Clinical Pharmacology, Peking University First Hospital, Peking University , Beijing , China jjxxeezz@163.com.
          Article
          10.1517/14728222.2015.1014803
          25677121

          Comments

          Comment on this article