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      Trace elements in the whale shark Rhincodon typus liver: an indicator of the health status of the ecosystem base (plankton)

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          Abstract

          ABSTRACT Trace elements were determined in three areas of the right (RL) and left (LL) lobe of the liver obtained from a whale shark (Rhincodon typus) stranded in Mexico. Mean ± standard error concentrations in μg g-1 wet weight were for zinc (Zn) RL: 22.5 ± 2.1; LL: 26.5 ± 7.1, arsenic (As) RL: 33.0 ± 1.6; LL: 20.0 ± 9.9 and cadmium (Cd) RL: 15.5 ± 0.9; LL: 11.3 ± 3.7; copper (Cu) RL: 3.2 ± 0.3; LL: 2.2 ± 0.8, selenium (Se) RL: 0.5 ± 0.1; LL: 1.2 ± 0.6, mercury (Hg) RL: 0.06 ± 0.02; LL: 0.05 ± 0.004 and lead (Pb) RL: 0.05 ± 0.02; LL: 0.05 ± 0.01. Concentrations showed significant (P < 0.05) differences within the same lobe but not between lobes. The trace element levels found in this whale shark represent the baseline levels of the trophic base's health status in the study area.

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          Cadmium: cellular effects, modifications of biomolecules, modulation of DNA repair and genotoxic consequences (a review).

          Cadmium is an important toxic environmental heavy metal. Occupational and environmental pollution with cadmium results mainly from mining, metallurgy industry and manufactures of nickel-cadmium batteries, pigments and plastic stabilizers. Important sources of human intoxication are cigarette smoke as well as food, water and air contaminations. In humans, cadmium exposures have been associated with cancers of the prostate, lungs and testes. Acute exposures are responsible for damage to these organs. Chronic intoxication is associated with obstructive airway disease, emphysema, irreversible renal failure, bone disorders and immuno-suppression. At the cellular level, cadmium affects proliferation, differentiation and causes apoptosis. It has been classified as a carcinogen by the International Agency for Research on Cancer (IARC). However, it is weakly genotoxic. Indirect effects of cadmium provoke generation of reactive oxygen species (ROS) and DNA damage. Cadmium modulates also gene expression and signal transduction, reduces activities of proteins involved in antioxidant defenses. Several studies have shown that it interferes with DNA repair. The present review focuses on the effects of cadmium in mammalian cells with special emphasis on the induction of damage to DNA, membranes and proteins, the inhibition of different types of DNA repair and the induction of apoptosis. Current data and hypotheses on the mechanisms involved in cadmium genotoxicity and carcinogenesis are outlined.
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            Molecular and cellular mechanisms of cadmium carcinogenesis

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              A review of the biology and ecology of the whale shark

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                Author and article information

                Journal
                lajar
                Latin american journal of aquatic research
                Lat. Am. J. Aquat. Res.
                Pontificia Universidad Católica de Valparaíso. Facultad de Recursos Naturales. Escuela de Ciencias del Mar (Valparaíso, , Chile )
                0718-560X
                May 2021
                : 49
                : 2
                : 359-364
                Affiliations
                [1] California Sur orgnameInstituto Politécnico Nacional La Paz orgdiv1Centro Interdisciplinario de Ciencias Marinas Mexico
                [2] Mazatlán orgnameUniversidad Nacional Autónoma de México orgdiv1Unidad Académica Mazatlán orgdiv2Instituto de Ciencias del Mar y Limnología Mexico
                [3] Sinaloa orgnameEl Colegio de Sinaloa Mexico
                Article
                S0718-560X2021000200359 S0718-560X(21)04900200359
                10.3856/vol49-issue2-fulltext-2535
                afb0d66a-de43-4748-81fe-a168206f6df7

                This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

                History
                : 10 November 2020
                : 06 April 2020
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 28, Pages: 6
                Product

                SciELO Chile

                Categories
                Short Communications

                Rhincodon typus,arsenic,mercury,selenium,cadmium molar ratio,Gulf of California

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