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      Retrospective analysis of snake victims in Northern India admitted in a tertiary level institute

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          Abstract

          Context:

          Snake bites are the common cause of morbidity and mortality in tropical countries.

          Aims:

          To analyze the outcome of snake bite victims

          Settings and Design:

          Retrospective analysis of data from Intensive care unit, Department of Anesthesiology.

          Materials and Methods:

          All the patients admitted in the intensive care unit for snake bite management during the year May 2004 - April 2009 were retrospectively reviewed. The data included age, sex, month and time of incident, site of bite, dose of anti--snake venom, time of anti--snake venom, administration, duration of mechanical ventilation, complications and death of a victim.

          Statistical analysis used:

          Pearson's correlation test, paired samples t-test.

          Results and Conclusions:

          113 patients reported to the Accident and Emergency with history of snake bite. 26 patients were referred to other hospital, 17 patients were brought dead, and 70 patients were admitted to the intensive care unit. In 59 snake-bite victims, maximum data could be recovered. Krait was the most common type of snake bite reported. There was a male preponderance (69.4%) with age ranging between 20 and 40 years (52.5%). The mean lag time (time elapsed between bite and first dose of anti--snake venom) was 5.3 ± 1.4 h and the mean anti-snake venom dose was 12.3 ± 2.4 vials. There was a positive and significant correlation between lag time and total dose of anti--snake venom (correlation coefficient =0.956, P<0.0001). Overall 72.9% patients required mechanical ventilation with a mean duration of 56.2 ± 16.1 h. 10.2% patients sustained cardiac arrest, 8.7% patients developed ventilator associated pneumonia, 6.7% suffered mild anti-snake venom reaction, 6.7% had hypotension and 5.1% patients developed renal failure. The overall mortality was 5.1%.

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          Most cited references21

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          Snake envenomation in a north Indian hospital.

          To study the clinical profile of snake envenomation in a tertiary referral north Indian hospital. Retrospective case note analysis of all cases of snakebite admitted to the medical emergency from January 1997 to December 2001. Of a total of 142 cases of snakebite there were 86 elapid bites presenting with neuroparalytic symptoms and 52 viper bites having haemostatic abnormalities. Some 60.6% of the cases of snakebite occurred when the patient was asleep. Urban to rural ratio was 1:4.7 and male to female ratio was 4.25:1. Median time to arrival at our hospital after the bite was nine hours and mean duration of hospital stay was eight days. Twenty seven cases had acute renal failure and 75% of all elapid bites required assisted ventilation. Seventeen of 119 patients who received antivenom had an adverse event. The average dose of antivenom was 51.2 vials for elapid bites and 31 vials for viper bites. Overall mortality rate was 3.5%. Snakebites are common in the rural population of developing countries. There is a need to educate the public about the hazards of snakebite, early hospital referral, and treatment.
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            Emergency treatment of a snake bite: Pearls from literature

            Snake bite is a well-known occupational hazard amongst farmers, plantation workers, and other outdoor workers and results in much morbidity and mortality throughout the world. This occupational hazard is no more an issue restricted to a particular part of the world; it has become a global issue. Accurate statistics of the incidence of snakebite and its morbidity and mortality throughout the world does not exist; however, it is certain to be higher than what is reported. This is because even today most of the victims initially approach traditional healers for treatment and many are not even registered in the hospital. Hence, registering such patients is an important goal if we are to have accurate statistics and reduce the morbidity and mortality due to snakebite. World Health Organization/South East Asian Region Organisation (WHO/SEARO) has published guidelines, specific for the South East Asian region, for the clinical management of snakebites. The same guidelines may be applied for managing snakebite patients in other parts of the world also, since no other professional body has come up with any other evidence-based guidelines. In this article we highlight the incidence and clinical features of different types of snakebite and the management guidelines as per the WHO/SEARO recommendation.
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              Government of India

              (1987)
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                Author and article information

                Journal
                J Anaesthesiol Clin Pharmacol
                JOACP
                Journal of Anaesthesiology, Clinical Pharmacology
                Medknow Publications & Media Pvt Ltd (India )
                0970-9185
                2231-2730
                Jan-Mar 2012
                : 28
                : 1
                : 45-50
                Affiliations
                [1]Department of Anesthesiology, JN Medical College, AMU, Aligarh, India
                [1 ]Department of Pulmonary medicine, SRMS, Bareilly, Uttar Pradesh, India
                Author notes
                Address for correspondence: Dr. Syed Moied Ahmed, Department of Anesthesiology, JN Medical College, AMU, Aligarh, 202 002, Uttar Pradesh, India. sma99@ 123456rediffmail.com
                Article
                JOACP-28-45
                10.4103/0970-9185.92434
                3275971
                22345945
                afc94694-ba1a-40c3-8f26-4c24be3391d9
                Copyright: © Journal of Anaesthesiology Clinical Pharmacology

                This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Categories
                Original Article

                Anesthesiology & Pain management
                anti-snake venom,snake-bite,lag time
                Anesthesiology & Pain management
                anti-snake venom, snake-bite, lag time

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