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      Left Atrial Appendage Blood Flow Determined by Transesophageal Echocardiography in Patients with Complete Atrioventricular Block

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          Abstract

          Function of the left atrial appendage (LAA) represented by LAA outflow is an important predictor for thrombus formation in patients with nonrheumatic atrial fibrillation, but the pattern of LAA flow in patients with complete atrioventricular (AV) block has rarely been studied. Twenty-one patients with complete AV block and an implanted WI or WIR pacemaker were studied with transesophageal echocardiography. The LAA outflow velocity obtained during the ventricular diastolic phase was significantly higher than that obtained during the ventricular systolic phase (41.5 ± 6.0vs. 34.9 ± 9.7cm/s; p < 0.001). The LAA inflow velocity obtained during the ventricular diastolic phase was also significantly higher than that obtained during the ventricular systolic phase (29.9 ± 7.8 vs. 26.4 ± 5.3 cm/s; p < 0.01). In addition, the LAA outflow and inflow velocity time integrals during the ventricular diastolic phase were significantly higher than those during the ventricular systolic phase (4.66 ± 0.96 vs. 4.08 ± 1.05 cm, p < 0.01, and 2.81 ± 0.77 vs. 2.56 ± 0.65 cm, p < 0.05, respectively). Thus, due to both diastolic augmentation of the LAA flow related to active atrial contraction and minor early diastolic LAA flow formation, left ventricle diastolic function might have some influence on LAA flow. This may have implications for the pathogenesis of LAA thrombi in left ventricular dysfunction.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1996
          1996
          19 November 2008
          : 87
          : 1
          : 71-75
          Affiliations
          Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan, ROC
          Article
          177063 Cardiology 1996;87:71–75
          10.1159/000177063
          8631049
          b0051839-cbed-49e0-bc8f-3ef5bb2b3fc9
          © 1996 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          : 23 November 1994
          : 31 March 1995
          Page count
          Pages: 5
          Categories
          Diagnostic and Noninvasive Cardiology

          General medicine,Neurology,Cardiovascular Medicine,Internal medicine,Nephrology
          Complete atrioventricular block,Left atrial appendage flow,Left ventricular relaxation

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