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      The multifarious, multireplicon Burkholderia cepacia complex.

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          Abstract

          The Burkholderia cepacia complex (Bcc) is a collection of genetically distinct but phenotypically similar bacteria that are divided into at least nine species. Bcc bacteria are found throughout the environment, where they can have both beneficial and detrimental effects on plants and some members can also degrade natural and man-made pollutants. Bcc bacteria are now recognized as important opportunistic pathogens that can cause variable lung infections in cystic fibrosis patients, which result in asymptomatic carriage, chronic infection or 'cepacia syndrome', which is characterized by a rapid decline in lung function that can include invasive disease. Here we highlight the unique characteristics of the Bcc, focusing on the factors that determine virulence.

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          Author and article information

          Journal
          Nat Rev Microbiol
          Nature reviews. Microbiology
          Springer Science and Business Media LLC
          1740-1526
          1740-1526
          Feb 2005
          : 3
          : 2
          Affiliations
          [1 ] Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3TL, UK.
          Article
          nrmicro1085
          10.1038/nrmicro1085
          15643431
          b00fa4c2-1e11-4350-9a0f-6d619cf9abef
          History

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