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      Increase of diesel car raises health risk in spite of recent development in engine technology

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          Abstract

          Diesel exhaust particles (DEP) contain elemental carbon, organic compounds including Polyaromatic hydrocarbons (PAHs), metals, and other trace compounds. Diesel exhaust is complex mixture of thousands of chemicals. Over forty air contaminants are recognized as toxicants, such as carcinogens. Most diesel exhaust particles have aerodynamic diameters falling within a range of 0.1 to 0.25 μm. DEP was classified as a definite human carcinogen (group 1) by the International Agency for Research on Cancer at 2012 based on recently sufficient epidemiological evidence for lung cancer. Significant decreases in DEP and other diesel exhaust constituents will not be evident immediately, and outworn diesel car having longer mileage still threatens health of people in spite of recent remarkable development in diesel engine technology. Policy change in South Korea, such as introduction of diesel taxi, may raise health risk of air pollution in metropolitan area with these limitations of diesel engine. To protect people against DEP in South Korea, progressive strategies are needed, including disallowance of diesel taxi, more strict regulation of diesel engine emission, obligatory diesel particulate filter attachment in outworn diesel car, and close monitoring about health effects of DEP.

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          Most cited references17

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          Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2009

          Purpose This study overviews nationwide cancer statistics, including incidence, mortality, survival, and prevalence, and their trends in Korea based on 2009 cancer incidence data. Materials and Methods Incidence data from 1993-2009 were obtained from the Korea National Cancer Incidence Database, and vital status was followed through 31 December 2010. Mortality data from 1983-2009 were obtained from Statistics Korea. Crude rates and age-standardized rates for incidence, mortality, and prevalence; and relative survival were calculated. Results In total, 192,561 cancer cases and 69,780 cancer deaths were observed during 2009, and 808,503 10-year cancer prevalent cases occurred in Korea as of 1 January 2010. The incidence rate for all cancers combined showed an annual increase of 3.3% from 1999 to 2009. Conclusion Stomach, liver and cervical cancers have been decreasing and thyroid, breast and colorectal cancers have been increasing at large. In particular, in 2009, colorectal cancer became the third most common cancer in females and for the first time ranked higher than stomach cancer, which had been the long-standing common cancer in Korea. While overall cancer incidence has been rapidly increasing in Korea, age-standardized cancer mortality rates have been declining since 2002, and cancer survival has been improving.
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            From particles to patients: oxidative stress and the cardiovascular effects of air pollution.

            Air pollution, especially airborne particulate matter (PM), is associated with an increase in both morbidity and mortality from cardiovascular disease, although the underlying mechanisms remain incompletely established. The one consistent observation that links the pulmonary and cardiovascular effects of inhaled PM is oxidative stress. This article examines the evidence for the role of oxidative stress in the cardiovascular effects of air pollution, beginning with observations from epidemiological and controlled exposure studies and then exploring potential mechanistic pathways involving free radical generation from PM itself, to effects of PM on cell cultures, isolated organs, healthy animals and animal models of disease. Particular emphasis is placed on the vascular and atherosclerotic effects of urban air pollution and diesel exhaust emissions as rich sources of environmental ultrafine particles.
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              OECD Health Data

              (2012)
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                Author and article information

                Journal
                Environ Health Toxicol
                Environ Health Toxicol
                EHT
                Environmental Health and Toxicology
                The Korean Society of Environmental Health and Toxicology
                2233-6567
                2014
                25 September 2014
                : 29
                : e2014009
                Affiliations
                [1 ]Department of Occupational & Environmental Medicine, Inha University School of Medicine, Incheon, Korea
                [2 ]Department of Environmental Engineering, University of Suwon, Suwon, Korea
                Author notes
                Correspondence: Jong Han Leem, MD, PhD 27 Inhang-ro, Jung-gu, Incheon 400-712, Korea  Tel: +82-32-890-3539 Fax: +82-32-890-2859 E-mail: ekeeper@ 123456inha.ac.kr
                Article
                eht-29-e2014009
                10.5620/eht.e2014009
                4207092
                25318659
                b0424ea1-62e2-4304-8c4f-e3450f0b4462
                Copyright © 2014 The Korean Society of Environmental Health and Toxicology

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 11 March 2014
                : 26 May 2014
                Categories
                Commentary

                Occupational & Environmental medicine
                air pollution,diesel engine technology,diesel exhaust particles,human carcinogen

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