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      Síndrome de Sjögren y endodoncia, consideraciones a propósito de un caso. Translated title: Sjögren's syndrome and endodontics, clinical case and considerations.


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          Resumen: El síndrome de Sjögren (SS) es una enfermedad autoinmune que afecta a las glándulas salivales y lagrimales. Se expone el caso clínico de una paciente de 67 años de género femenino que consulta por dolor en múltiples dientes; relata sensación de boca seca (xerostomía) y sequedad ocular (xeroftalmia). Al examen intraoral, se observan múltiples caries en superficies atípicas, mucosas secas, saliva espumosa y notoria depapilación lingual. Se sospecha de SS, derivando a medicina interna y confirmándose el diagnóstico. En paralelo, se inicia el tratamiento odontológico, realizando adaptaciones en los procedimientos para aliviar la sintomatología del SS, especialmente durante tratamientos endodónticos.

          Translated abstract

          Abstract: Sjögren's syndrome (SS) is an autoimmune disease that affects the salivary and lacrimal glands. The clinical case of a 67-year-old female patient who consulted for pain in multiple teeth is exposed. Additionally, she reports a sensation of dry mouth (xerostomia) and dry eyes (xerophthalmia). During the intraoral examination, the following findings are noticed: multiple cavities on atypical surfaces, dry mucous membranes, foamy saliva, and atrophic glossitis. SS is suspected, referring to internal medicine and confirming the diagnosis. In parallel, dental treatment is initiated, making adaptations in the procedures to alleviate the symptoms of SS, especially during endodontic treatments.

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          Sjogren’s syndrome: An update on disease pathogenesis, clinical manifestations and treatment

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            Current concepts on Sjögren's syndrome – classification criteria and biomarkers

            Sjögren's syndrome is a lymphoproliferative disease with autoimmune features characterized by mononuclear cell infiltration of exocrine glands, notably the lacrimal and salivary glands. These lymphoid infiltrations lead to dryness of the eyes (keratoconjunctivitis sicca), dryness of the mouth (xerostomia), and, frequently, dryness of other surfaces connected to exocrine glands. Sjögren's syndrome is associated with the production of autoantibodies because B‐cell activation is a consistent immunoregulatory abnormality. The spectrum of the disease extends from an organ‐specific autoimmune disorder to a systemic process and is also associated with an increased risk of B‐cell lymphoma. Current treatments are mainly symptomatic. As a result of the diverse presentation of the syndrome, a major challenge remains to improve diagnosis and therapy. For this purpose an international set of classification criteria for primary Sjögren's syndrome has recently been developed and validated and seems well suited for enrolment in clinical trials. Salivary gland biopsies have been examined and histopathology standards have been developed, to be used in clinical trials and patient stratification. Finally, ultrasonography and saliva meet the need of non‐invasive imaging and sampling methods for discovery and validation of disease biomarkers in Sjögren's syndrome.
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              Caries management by risk assessment.

              Caries disease is multifactorial. Whether caries disease will be expressed and damage dental hard tissue is dependent on the patient's own unique make-up of pathogenic risk factors and protective factors. Objectives This manuscript will review the science of managing caries disease based on assessing caries risk. Methods The caries balance/imbalance model and a practical caries risk assessment procedure for patients aged 6 years through adult will illustrate how treatment options can be based on caries risk. Results Neither the forms nor the clinical protocols are meant to imply there is currently only one correct way this can be achieved, rather are used in this manuscript as examples only. Conclusions It is important to have the forms and protocols simple and easy to understand when implementing caries management by risk assessment into clinical practice. The science of CAMBRA based on the caries balance/imbalance model was reviewed and an example protocol was presented.

                Author and article information

                ARS medica (Santiago)
                ARS med. (Santiago)
                Pontificia Universidad Católica de Chile. Facultad de Medicina. (Santiago, , Chile )
                December 2023
                : 48
                : 4
                : 49-53
                [1] Santiago Santiago de Chile orgnamePontificia Universidad Católica de Chile orgdiv1Facultad de Medicina orgdiv2Escuela de Odontología Chile
                S0719-18552023000400049 S0719-1855(23)04800400049

                This work is licensed under a Creative Commons Attribution 4.0 International License.

                : 11 October 2022
                : 07 September 2023
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 9, Pages: 5

                SciELO Chile

                CASOS CLINICOS

                autoimmune diseases,Sjogren's syndrome,dentistry,endodontics,root canal treatment, clinical considerations,enfermedades autoinmunes,síndrome de Sjögren,odontología,endodoncia,tratamiento de canales radiculares,consideraciones clínicas


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