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      Drug Design, Development and Therapy (submit here)

      This international, peer-reviewed Open Access journal by Dove Medical Press focuses on the design and development of drugs, as well as the clinical outcomes, patient safety, and programs targeted at the effective and safe use of medicines. Sign up for email alerts here.

      88,007 Monthly downloads/views I 4.319 Impact Factor I 6.6 CiteScore I 1.12 Source Normalized Impact per Paper (SNIP) I 0.784 Scimago Journal & Country Rank (SJR)

       

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      Tongguan capsule ameliorates coronary artery stenosis in a 40-year-old woman

      case-report

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          Abstract

          Cardiovascular disease is the leading cause of death worldwide, with coronary heart disease as the major contributor to this related mortality. There is a growing trend in the application of Chinese medicine in clinical practice for the treatment of coronary heart disease. However, there is a lack of knowledge surrounding the pharmacological, toxicological, and biological profiles of Chinese medicine. In this case report, we describe the therapeutic effects of Tongguan capsule in a 40-year-old woman diagnosed with stable angina pectoris. To the best of the authors’ knowledge, this is the first case documented of the therapeutic effect of Tongguan capsule in the treatment of coronary heart disease.

          Most cited references19

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          Cardiovascular effects of Danshen.

          Tsung Cheng (2007)
          Danshen is one of the most versatile Chinese herbal drugs that have been used for hundred of years in the treatment of numerous ailments. Because of its properties of improving microcirculation, causing coronary vasodilatation, suppressing the formation of thromboxane, inhibiting platelet adhesion and aggregation, and protecting against myocardial ischemia, it is widely used either alone or in combination with other herbal ingredients for patients with coronary artery disease and other cardiovascular diseases, in both China and other countries including the United States. This article provides an overview of its history, pharmacology, pharmacokinetics, clinical applications, side effects, interactions with Western drugs, and future prospects in the management of cardiovascular diseases.
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            Deaths: Final Data for 2013.

            Jiaquan Xu, Sherry Murphy, Kenneth Kochanek … (2016)
            This report presents final 2013 data on U.S. deaths, death rates, life expectancy, infant mortality, and trends, by selected characteristics such as age, sex, Hispanic origin, race, state of residence, and cause of death.
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              Pharmaceutical properties of calycosin, the major bioactive isoflavonoid in the dry root extract of Radix astragali.

              JunQing Gao, Zong Liu, Tao Chen … (2014)
              Radix astragali (Fabaceae astragalus propinquus Schischkin) is a Chinese medicinal herb traditionally used for the treatment of several diseases. Calycosin is the major bioactive chemical in the dry root extract of this medical plant.
              Article 0 comments Cited 40 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (nlm-ta): Drug Des Devel Ther
                Journal ID (iso-abbrev): Drug Des Devel Ther
                Journal ID (publisher-id): Drug Design, Development and Therapy
                Title: Drug Design, Development and Therapy
                Publisher: Dove Medical Press
                ISSN (Electronic): 1177-8881
                Publication date Collection: 2015
                Publication date (Electronic): 10 August 2015
                Volume: 9
                Pages: 4413-4416
                Affiliations
                [1 ]Department of Critical Care Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangdong, People’s Republic of China
                [2 ]Department of Critical Care Medicine, Guangdong General Hospital, Guangdong, People’s Republic of China
                [3 ]Medical Imaging Central, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, Guangdong, People’s Republic of China
                Author notes
                Correspondence: Minzhou Zhang, Department of Critical Care Medicine, Guangdong Provincial Hospital of Chinese Medicine, 111 Dade Road, Yuexiu, Guangzhou, Guangdong 510120, People’s Republic of China, Tel +86 20 8188 7233, Fax +86 20 8188 7233, Email mahuannovel@ 123456163.com
                Article
                Publisher ID: dddt-9-4413
                DOI: 10.2147/DDDT.S85571
                PMC ID: 4539080
                SO-VID: b0a131b2-613b-4223-9577-d46501108d8c
                Copyright © © 2015 Ma et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License
                License:

                The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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                Categories
                Subject: Case Report

                ScienceOpen disciplines: Pharmacology & Pharmaceutical medicine
                Keywords: chinese medicine,tongguan capsule,cardiovascular disease,stable angina pectoris
                Data availability:
                ScienceOpen disciplines: Pharmacology & Pharmaceutical medicine
                Keywords: chinese medicine, tongguan capsule, cardiovascular disease, stable angina pectoris

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