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      Noradrenaline Content and Release in the Mesenteric Artery of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) and a New Strain of SHRSP (M-SHRSP)

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          Abstract

          Adrenergic innervation in the main trunk of the mesenteric artery was studied in stroke-prone spontaneously hypertensive rats (SHRSP) as well as in a new strain of SHRSP (M-SHRSP) and was compared with that of normotensive Wistar Kyoto rats (WKY). Noradrenaline (NA) content and high K-induced NA release in the artery of 6-week-old SHRSP and M-SHRSP were greater than those in the artery of WKY. These results suggest that a higher adrenergic innervation of the artery might be involved in the development of hypertension in SHRSP and M-SHRSP.

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          Author and article information

          Journal
          JVR
          J Vasc Res
          10.1159/issn.1018-1172
          Journal of Vascular Research
          S. Karger AG
          1018-1172
          1423-0135
          1987
          1987
          23 September 2008
          : 24
          : 6
          : 334-338
          Affiliations
          Research Institute of Hypertension, Kinki University, Osaka, Japan
          Article
          158710 Blood Vessels 1987;24:334–338
          10.1159/000158710
          © 1987 S. Karger AG, Basel

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          Page count
          Pages: 5
          Categories
          Research Paper

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