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      Noradrenaline Content and Release in the Mesenteric Artery of Stroke-Prone Spontaneously Hypertensive Rats (SHRSP) and a New Strain of SHRSP (M-SHRSP)

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          Adrenergic innervation in the main trunk of the mesenteric artery was studied in stroke-prone spontaneously hypertensive rats (SHRSP) as well as in a new strain of SHRSP (M-SHRSP) and was compared with that of normotensive Wistar Kyoto rats (WKY). Noradrenaline (NA) content and high K-induced NA release in the artery of 6-week-old SHRSP and M-SHRSP were greater than those in the artery of WKY. These results suggest that a higher adrenergic innervation of the artery might be involved in the development of hypertension in SHRSP and M-SHRSP.

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          Author and article information

          J Vasc Res
          Journal of Vascular Research
          S. Karger AG
          23 September 2008
          : 24
          : 6
          : 334-338
          Research Institute of Hypertension, Kinki University, Osaka, Japan
          158710 Blood Vessels 1987;24:334–338
          © 1987 S. Karger AG, Basel

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          Pages: 5
          Research Paper


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