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      Gastroesophageal reflux in young children and adolescents: Is there a relation between symptom severity and esophageal histological grade?

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          Abstract

          The pediatric literature about the correlation between symptoms and histological lesions in patients investigated for gastroesophageal reflux disease is scarce and inconclusive. The primary aim of the present study was to assess the relation between the complained symptom severity and the esophageal histological grade, through the use of validated and reliable scores.

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          Author and article information

          Journal
          J Pediatr Gastroenterol Nutr
          Journal of pediatric gastroenterology and nutrition
          Ovid Technologies (Wolters Kluwer Health)
          1536-4801
          0277-2116
          Mar 2015
          : 60
          : 3
          Affiliations
          [1 ] *Department of Translational Medical Science, Section of Pediatrics, University of Naples "Federico II", Naples †Department of Pediatrics, "La Sapienza" University, Rome ‡Department of Advanced Biomedical Sciences, Section of Pathology, University of Naples, Naples §Department of Radiological Sciences, Oncology, and Anatomical Pathology, "La Sapienza" University, Rome, Italy.
          Article
          10.1097/MPG.0000000000000614
          25373865
          b0c680a3-8908-4af6-8876-b41c750b2344
          History

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