Peng Yan: Role: Data curationRole: InvestigationRole: Methodology
Ken Chen: Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole:
MethodologyRole: Writing – original draftRole: Writing – review & editing
Qiang Wang: Role: Formal analysisRole: Funding acquisition
Dachun Yang: Role: Funding acquisition
De Li: Role: Project administrationRole: Resources
Yongjian Yang:
ORCID: http://orcid.org/0000-0002-0077-6568
Role: ConceptualizationRole: Funding acquisitionRole: Project administrationRole:
Writing – review & editing
Harald HHW Schmidt: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
6
July
2017
Publication date Collection: 2017
Volume: 12
Issue: 7
Electronic Location Identifier: e0179743
Affiliations
[001]Department of Cardiology, Chengdu Military General Hospital, Chengdu, Sichuan, P.R.
China
Maastricht University, NETHERLANDS
Author notes
Competing Interests: The authors have declared that no competing interests exist.
‡ These authors are co-first authors on this work.
Author information
Article
Publisher ID:
PONE-D-17-01922
DOI: 10.1371/journal.pone.0179743
PMC ID: 5500278
PubMed ID: 28683125
SO-VID: b0d1ce7f-b06e-49d2-85f3-7ae31c7e86da
Copyright © © 2017 Yan et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: funder-id http://dx.doi.org/10.13039/501100001809, National Natural Science Foundation of China;
Award ID: 81500224
Award Recipient
:
Qiang Wang
Funded by: funder-id http://dx.doi.org/10.13039/501100001809, National Natural Science Foundation of China;
Award ID: 81670419
Award Recipient
:
ORCID: http://orcid.org/0000-0002-0077-6568
Yongjian Yang
Funded by: China Postdoctoral Science Foundation funded project
Award ID: 2016M593044
Award Recipient
:
Qiang Wang
Funded by: funder-id http://dx.doi.org/10.13039/501100001809, National Natural Science Foundation of China;
Award ID: 81470396
Award Recipient
:
Dachun Yang
These studies were supported in part by grants from National Natural Science Foundation
of China (no. 81500224; 81670419; 81470396), China Postdoctoral Science Foundation
funded project (no. 2016M593044). The funders had no role in study design, data collection
and analysis, decision to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cell Processes
Subject:
Cell Death
Subject:
Apoptosis
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Cardiovascular Anatomy
Subject:
Blood Vessels
Subject:
Aorta
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Cardiovascular Anatomy
Subject:
Blood Vessels
Subject:
Aorta
Subject:
Medicine and Health Sciences
Subject:
Vascular Medicine
Subject:
Vascular Diseases
Subject:
Aneurysms
Subject:
Biology and Life Sciences
Subject:
Molecular Biology
Subject:
Molecular Biology Techniques
Subject:
Molecular Biology Assays and Analysis Techniques
Subject:
Gene Expression and Vector Techniques
Subject:
Protein Expression
Subject:
Research and Analysis Methods
Subject:
Molecular Biology Techniques
Subject:
Molecular Biology Assays and Analysis Techniques
Subject:
Gene Expression and Vector Techniques
Subject:
Protein Expression
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Antioxidants
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Bioenergetics
Subject:
Energy-Producing Organelles
Subject:
Mitochondria
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Structures and Organelles
Subject:
Energy-Producing Organelles
Subject:
Mitochondria
Subject:
Biology and Life Sciences
Subject:
Molecular Biology
Subject:
Molecular Biology Techniques
Subject:
Molecular Probe Techniques
Subject:
Immunoblotting
Subject:
Research and Analysis Methods
Subject:
Molecular Biology Techniques
Subject:
Molecular Probe Techniques
Subject:
Immunoblotting
Subject:
Research and Analysis Methods
Subject:
Specimen Preparation and Treatment
Subject:
Staining
Subject:
Group-Specific Staining
Subject:
Hematoxylin Staining