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Genital vitiligo treated by autologous, noncultured melanocyte-keratinocyte cell transplantation.

Dermatologic Surgery

surgery, Adult, Cell Transplantation, methods, Humans, Keratinocytes, transplantation, Male, Melanocytes, Penis, Skin Transplantation, Transplantation, Autologous, Vitiligo

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      Genital vitiligo is common and has a deleterious effect on the psychosexual function of patients. It is well known that glabrous skin (non-hair-bearing skin such as below the ankles, genitalia, lips, distal ends of fingers) rarely responds to the therapy unless it has some residual pigment. The objective was to report genital vitiligo treated successfully by autologous, noncultured, melanocyte-keratinocyte cell transplantation. Three cases of clinically stable genital vitiligo were treated by autologous, noncultured melanocyte-keratinocyte cell transplantation. All lesions treated repigmented almost completely. All patients were very satisfied with the excellent cosmetic results. Autologous, noncultured melanocyte-keratinocyte cell transplantation may be an effective surgical treatment for management of genital vitiligo.

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