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      Pulmonary Function Tests in Patients with Congestive Heart Failure: Effects of Medical Therapy

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          Abstract

          In a group of 13 patients with severe heart failure, both forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV1) significantly improved after intensive medical therapy (FVC: from 77 ± 17 to 92 ± 20%, p < 0.001; FEV1: from 65 ± 15 to 81 ± 15%, p < 0.001) in the absence of change in M-mode echo cardiac dimension and left ventricular systolic function; on the other hand, a change of indices of left ventricular filling by Doppler transmitral flow was documented (E/A ratio: from 3.6 ± 1.2 to 1.65 ± 1.5, p < 0.01; early filling deceleration time: from 94 ± 39 to 178 ± 78 ms, p < 0.01), indicating a reduction of pulmonary capillary pressure; this probably positively affected pulmonary interstitial edema and bronchial wall congestion, thus enhancing pulmonary function.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1993
          1993
          14 November 2008
          : 83
          : 1-2
          : 30-35
          Affiliations
          aDivision of Cardiology and bInternal Medicine, S. Orsola Hospital, Brescia, Italy
          Article
          175944 Cardiology 1993;83:30–35
          10.1159/000175944
          8261483
          © 1993 S. Karger AG, Basel

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          Page count
          Pages: 6
          Categories
          General Cardiology

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