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      The Management of Isolated Renal Recurrence of Renal Cell Carcinoma Following Complete Response to Interleukin-2 Based Immunotherapy

      , , , ,
      The Journal of Urology
      Elsevier BV

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          Abstract

          The role of interleukin-2 based immunotherapy in advanced renal cell carcinoma is gradually expanding. Among patients who achieve significant responses to these regimens the subsequent development of isolated recurrences raises difficult management questions. We report 2 unusual cases of isolated recurrence in the remaining kidney following a sustained, complete response to interleukin-2 based adoptive immunotherapy. Both patients were treated with interleukin-2 based therapy following surgical resection of the primary renal tumor. The disease course of each patient is described and the literature is reviewed. Both patients were free of disease after relatively short-term followup. Surgery for patients with limited recurrence of renal cell carcinoma following an objective response to immunotherapy may, in select cases, be a reasonable treatment alternative.

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          Author and article information

          Journal
          The Journal of Urology
          The Journal of Urology
          Elsevier BV
          00225347
          July 1993
          July 1993
          : 150
          : 1
          : 176-178
          Article
          10.1016/S0022-5347(17)35428-9
          8510245
          b15411c0-3230-45a1-9608-4e2239514f41
          © 1993

          https://www.elsevier.com/tdm/userlicense/1.0/

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