56
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Social relationships and risk of dementia: A systematic review and meta-analysis of longitudinal cohort studies.

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          It is unclear to what extent poor social relationships are related to the development of dementia. A comprehensive systematic literature search identified 19 longitudinal cohort studies investigating the association between various social relationship factors and incident dementia in the general population. Relative risks (RRs) with 95% confidence intervals (CIs) were pooled using random-effects meta-analysis. Low social participation (RR: 1.41 (95% CI: 1.13-1.75)), less frequent social contact (RR: 1.57 (95% CI: 1.32-1.85)), and more loneliness (RR: 1.58 (95% CI: 1.19-2.09)) were statistically significant associated with incident dementia. The results of the association between social network size and dementia were inconsistent. No statistically significant association was found for low satisfaction with social network and the onset of dementia (RR: 1.25 (95% CI: 0.96-1.62). We conclude that social relationship factors that represent a lack of social interaction are associated with incident dementia. The strength of the associations between poor social interaction and incident dementia is comparable with other well-established risk factors for dementia, including low education attainment, physical inactivity, and late-life depression.

          Related collections

          Author and article information

          Journal
          Ageing Res. Rev.
          Ageing research reviews
          Elsevier BV
          1872-9649
          1568-1637
          Jul 2015
          : 22
          Affiliations
          [1 ] Department of Epidemiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands. Electronic address: j.s.kuiper@umcg.nl.
          [2 ] Department of Psychiatry, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands. Electronic address: m.zuidersma@umcg.nl.
          [3 ] Department of Psychiatry, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands. Electronic address: r.c.oude.voshaar@umcg.nl.
          [4 ] Department of General Practice, University of Groningen, University Medical Center Groningen, Hanzeplein 1, Postbus 196, HPC FA21, 9700 AD Groningen, The Netherlands. Electronic address: s.u.zuidema@umcg.nl.
          [5 ] Department of Epidemiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands; Department of Mathematics and Computer Science, Eindhoven University of Technology, Postbus 513, 5600 MB, Eindhoven, The Netherlands. Electronic address: e.r.v.d.heuvel@tue.nl.
          [6 ] Department of Epidemiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands. Electronic address: r.p.stolk@umcg.nl.
          [7 ] Department of Epidemiology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands. Electronic address: n.smidt@umcg.nl.
          Article
          S1568-1637(15)00046-X
          10.1016/j.arr.2015.04.006
          25956016
          b185b6d4-b572-4444-9680-12abf6c1c6bb
          History

          Dementia,Loneliness,Social contact,Social network,Social participation,Social relationships

          Comments

          Comment on this article