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      Low-dose Spironolactone: Treatment for Osteoarthritis-related Knee Effusion. A Prospective Clinical and Sonographic-based Study.

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          Abstract

          To evaluate the effectiveness of spironolactone as a treatment for osteoarthritis (OA)-related knee effusion in comparison to ibuprofen, cold compresses, and placebo.

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          Author and article information

          Journal
          J. Rheumatol.
          The Journal of rheumatology
          The Journal of Rheumatology
          0315-162X
          0315-162X
          Jun 2016
          : 43
          : 6
          Affiliations
          [1 ] From the Department of Rheumatology and Rehabilitation, and the Department of Pharmacology, Faculty of Medicine, Sohag University, Sohag, Egypt; Department of Rheumatology and Clinical Immunology, Charité Universitätsmedizin, Berlin, Germany.A.M. Elsaman, MD, Lecturer of Rheumatology, Department of Rheumatology and Rehabilitation, Faculty of Medicine, Sohag University; A.R. Radwan, MD, Lecturer of Rheumatology, Department of Rheumatology and Rehabilitation, Faculty of Medicine, Sohag University; W.I. Mohammed, MD, Lecturer of Pharmacology, Department of Pharmacology, Faculty of Medicine, Sohag University; S. Ohrndorf, MD, Specialist in Internal Medicine/Rheumatology, Department of Rheumatology and Clinical Immunology, Charité Universitätsmedizin.
          [2 ] From the Department of Rheumatology and Rehabilitation, and the Department of Pharmacology, Faculty of Medicine, Sohag University, Sohag, Egypt; Department of Rheumatology and Clinical Immunology, Charité Universitätsmedizin, Berlin, Germany.A.M. Elsaman, MD, Lecturer of Rheumatology, Department of Rheumatology and Rehabilitation, Faculty of Medicine, Sohag University; A.R. Radwan, MD, Lecturer of Rheumatology, Department of Rheumatology and Rehabilitation, Faculty of Medicine, Sohag University; W.I. Mohammed, MD, Lecturer of Pharmacology, Department of Pharmacology, Faculty of Medicine, Sohag University; S. Ohrndorf, MD, Specialist in Internal Medicine/Rheumatology, Department of Rheumatology and Clinical Immunology, Charité Universitätsmedizin. sarah.ohrndorf@charite.de.
          Article
          jrheum.151200
          10.3899/jrheum.151200
          27036390
          b19fa108-ee38-40e7-aa91-fbc0b5acdf4f
          History

          KNEE EFFUSION,MUSCULOSKELETAL ULTRASONOGRAPHY,OSTEOARTHRITIS,SPIRONOLACTONE

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