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      Systolic Time Intervals in Isolated Septal Defects before and after Corrective Surgery in Female Patients

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          Systolic time intervals (STI) were evaluated in 19 female patients with uncomplicated ostium secundum atrial septal defect (ASD), before, shortly after (within 2 months) and a long time after the corrective surgery (mean 13.2 years). The measurements were obtained from simultaneous high speed photographic recordings of electrocardiogram, external carotid pulse and phonocardiogram. Before the operation, a significant prolongation of Q-I heart sound interval was detected, together with a less prominent but statistically significant shortening of the left ventricular ejection time; the above alterations were not correlated with the magnitude of the shunt and disappeared shortly after corrective surgery. The STI were still normal a long time after surgical closure of ASD. In accordance with hemodynamic studies reported by other authors, our results confirm that the deviations of STI observed in ASD are due to a reduced diastolic filling of the left ventricle secondary to an apparent decreased distensibility.

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          Author and article information

          S. Karger AG
          11 November 2008
          : 71
          : 1
          : 48-53
          Istituto di Patologia Speciale Medica e Metodologia Clinica, Sezione di Cardiologia, Università di Modena, Italia
          173648 Cardiology 1984;71:48–53
          © 1984 S. Karger AG, Basel

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          Pages: 6
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