8
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Polysaccharide hydrogels for modified release formulations.

      Journal of Controlled Release
      Animals, Chemistry, Pharmaceutical, Delayed-Action Preparations, Drug Delivery Systems, methods, Humans, Hydrogels, administration & dosage, chemistry, Polysaccharides

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Hydrogels are three-dimensional, hydrophilic, polymeric networks, with chemical or physical cross-links, capable of imbibing large amounts of water or biological fluids. Among the numerous macromolecules that can be used for hydrogel formation, polysaccharides are extremely advantageous compared to synthetic polymers being widely present in living organisms and often being produced by recombinant DNA techniques. Coming from renewable sources, polysaccharides also have frequently economical advantages over synthetic polymers. Polysaccharides are usually non-toxic, biocompatible and show a number of peculiar physico-chemical properties that make them suitable for different applications in drug delivery systems. We review here a selection of the most important polysaccharides that have been studied and exploited in several fields related to pharmaceutics. Particular attention has been focused on the techniques used for the hydrogel network preparation, on the drug delivery results, on clinical applications as well as on the possible use of such systems as scaffolds for tissue engineering.

          Related collections

          Author and article information

          Journal
          17382422
          10.1016/j.jconrel.2007.01.004

          Chemistry
          Animals,Chemistry, Pharmaceutical,Delayed-Action Preparations,Drug Delivery Systems,methods,Humans,Hydrogels,administration & dosage,chemistry,Polysaccharides

          Comments

          Comment on this article