Correction: Fluoride Regulate Osteoblastic Transforming Growth Factor-β1 Signaling by Mediating Recycling of the Type I Receptor ALK5

Abstract

In Fig 2, the y-axis for the graphs Runx2 and RANKL are incorrectly labeled. The axis should be labeled “Rative RNA abundance” Please see the corrected Fig 2 here. 10.1371/journal.pone.0176772.g001 Fig 2 Gene expression of Runx2, RANKL, Smad3 and ALK5 in rats treated by fluoride with or without SB431542. Rats was treated with sodium fluoride by gavage at 10 mgF-/kg.bw and 20 mgF-/kg.bw for 2 months, and half of rats in each group were injected with an ALK5 inhibitor (SB431542, 2.1 mg/kg.bw). The femurs were collected and extracted mRNA by Trizol reagent. Realtime PCR was used to analyze Runx2, RANKL, Smad3 and ALK5 expression. Results are expressed as mean± SD(n = 3). (**P < 0.01 compare with control group; aa P < 0.01, compare with two groups). In S1 File, the data for Runx2 and RANKL is incorrect. Please see the corrected S1 File here. Supporting information S1 File All raw data used for drawing result figures. (XLSX) Click here for additional data file.