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Rearrangement of atrial bundle architecture and consequent changes in anisotropy of conduction constitute the 3-dimensional substrate for atrial fibrillation.
Bart Maesen
1 ,
Stef Zeemering ,
Carlos Afonso ,
Jens Eckstein ,
Rebecca A B Burton ,
Arne van Hunnik ,
Daniel J Stuckey ,
Damian Tyler ,
Jos Maessen ,
Vicente Grau ,
Sander Verheule ,
Peter Kohl ,
Ulrich Schotten
Oct 2013
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Abstract
Anisotropy of conduction facilitates re-entry and is, therefore, a key determinant of the stability of atrial fibrillation (AF). Little is known about the effect of AF on atrial bundle architecture and consequent changes in anisotropy of conduction and maintenance of AF.