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      Labour analgesia and anaesthetic management of a primigravida with uncorrected pentalogy of fallot: Few concerns

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          Abstract

          Sir, We read the case report, ‘Labour analgesia and anaesthetic management of a primigravida with uncorrected pentalogy of Fallot,’ by Dr. K. Sandhya et al.,[1] with interest. We congratulate the authors for the successful management and the nice description of such a challenging case. However, certain points regarding the management of this case are worth mentioning. Infective endocarditis prophylaxis should have been administered one hour before the procedure. Any patient with uncorrected acyanotic heart disease undergoing genitourinary procedure should receive infective endocarditis prophylaxis.[2] The authors mentioned ‘full cardiac monitoring,’ but did not mention any invasive monitoring used during the vulval hematoma drainage, under epidural anaesthesia. In a term pregnancy, the systemic vascular resistance (SVR) decreases by 20%. Further reduction of SVR by epidural local anaesthetics can cause hypotension and further worsen the right-to-left shunt, already present in Tetralogy/Pentalogy of Fallot. Monitoring of arterial blood pressure can help in titrating epidural local anaesthetics and managing haemodynamic alterations, with the timely use of a vasopressor, and performing arterial blood gas analysis in case of worsening cyanosis or a cyanotic spell.[3 4] The authors mentioned about the ‘minimisation of sympathetic blockade by maintaining intravascular volume,’ but did not mention if any vasopressor was used or kept ready. Any degree of sympathetic blockade would decrease the SVR and could worsen the right-to-left shunt in such patients. Phenylephrine is considered to be the vasopressor of choice. It should be kept ready and used at the earliest.[3 5] The authors mentioned that 10 units of oxytocin were used during labour. However, they did not discuss the adverse effects of oxytocin on the Fallot physiology. Oxytocin (particularly if given as a bolus) caused peripheral vasodilation and a decrease in SVR, thereby increasing the chance of worsening of the right-to-left shunt. We presume that it was given as slow infusion.[6] Air embolism is a serious concern in such patients. All intravenous lines used in such patients should be equipped with a device to filter air bubbles, to prevent paradoxical air embolism.[3]

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          Haemodynamic effects of oxytocin given as i.v. bolus or infusion on women undergoing Caesarean section.

          The cardiovascular effects of oxytocin in animal models and women undergoing Caesarean section include tachycardia, hypotension and decrease in cardiac output. These can be sufficient to cause significant compromise in high-risk patients. We aimed to find a simple way to decrease these risks whilst retaining the benefits of oxytocin in decreasing bleeding after delivery. Method. We recruited 30 women undergoing elective Caesarean section. They were randomly allocated to receive 5 u of oxytocin either as a bolus injection (bolus group) or an infusion over 5 min (infusion group). These women had their heart rate and intra-arterial blood pressure recorded every 5 s throughout the procedure. The haemodynamic data, along with the estimated blood loss, were compared between the groups. Marked cardiovascular changes occurred in the bolus group; the heart rate increased by 17 (10.7) beats min(-1) [mean (sd)] compared with 10 (9.7) beats min(-1) in the infusion group. The mean arterial pressure decreased by 27 (7.6) mm Hg in the bolus group compared with 8 (8.7) mm Hg in the infusion group. There were no differences in the estimated blood loss between the two groups. We recommend that bolus doses should be used with caution, and further studies should ascertain if oxytocin is equally effective in reducing blood loss when given at a slower rate.
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            Low-dose sequential combined-spinal epidural anesthesia for Cesarean section in patient with uncorrected tetrology of Fallot

            Tetrology of Fallot (TOF) is the most commonly encountered congenital cardiac lesion in pregnancy. Although there are controversies regarding safe anesthetic technique for parturient with TOF, we use low-dose sequential combined-spinal epidural anesthesia in such a case posted for Cesarean section and found that low dose (0.5 ml of 0.5%) intrathecal bupivacaine and fentanyl with sequential epidural bupivacaine supplementation was adequate for the performance of an uncomplicated Cesarean section with minimal side effects and good fetal outcome. Thus, though the choice of anesthesia can vary in such patients, low-dose sequential combined-spinal epidural can be a safe alternate to achieve good anesthesia with impressive cardiovascular stability.
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              Central neuraxial anesthesia for caesarean section in parturients with uncorrected tetralogy of fallot: two cases

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                Author and article information

                Journal
                Indian J Anaesth
                Indian J Anaesth
                IJA
                Indian Journal of Anaesthesia
                Medknow Publications & Media Pvt Ltd (India )
                0019-5049
                0976-2817
                Jan-Feb 2013
                : 57
                : 1
                : 102-103
                Affiliations
                [1]Department of Anaesthesia and Intensive Care, All India Institute of Medical Sciences, New Delhi, India
                Author notes
                Address for correspondence: Dr. Dalim Kumar Baidya, Department of Anaesthesia and Intensive Care, Fifth Floor, Teaching Block, All India Institute of Medical Sciences, New Delhi, India. E-mail: dalimkumar.ab8@ 123456gmail.com
                Article
                IJA-57-102
                10.4103/0019-5049.108598
                3658324
                23716792
                b2e58dc5-5835-4dd2-b2e7-6b779c1c6268
                Copyright: © Indian Journal of Anaesthesia

                This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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                Anesthesiology & Pain management
                Anesthesiology & Pain management

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