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      Altered cerebral inhibition of respiratory and cardiac responses to hypercapnia in acute stroke.

      Neurology

      Tidal Volume, Adolescent, Adult, Aged, Carbon Dioxide, blood, physiology, Cerebral Infarction, complications, physiopathology, Heart Rate, Humans, Hypercapnia, Middle Aged, Oxygen, Respiration

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          Abstract

          Ventilatory and heart-rate responses to hypercapnia were evaluated by a CO2 rebreathing technique in 56 patients with acute ischemic stroke and 14 normal controls. Both ventilatory and heart-rate responses were increased in patients with hemispheral lesions, but not in patients with brainstem lesions. In patients with hemispheral infarct, there was a decrease in CO2 sensitivity 1 to 3 weeks later. Acute hemisphere lesions may result in a transient decrease of cerebral inhibition of brainstem-mediated autonomic responses to a chemical stimulus.

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          6775248

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