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      Movement Disorders Society Scientific Issues Committee report: SIC Task Force appraisal of clinical diagnostic criteria for Parkinsonian disorders.

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          Abstract

          As there are no biological markers for the antemortem diagnosis of degenerative parkinsonian disorders, diagnosis currently relies upon the presence and progression of clinical features and confirmation depends on neuropathology. Clinicopathologic studies have shown significant false-positive and false-negative rates for diagnosing these disorders, and misdiagnosis is especially common during the early stages of these diseases. It is important to establish a set of widely accepted diagnostic criteria for these disorders that may be applied and reproduced in a blinded fashion. This review summarizes the findings of the SIC Task Force for the study of diagnostic criteria for parkinsonian disorders in the areas of Parkinson's disease, dementia with Lewy bodies, progressive supranuclear palsy, multiple system atrophy, and corticobasal degeneration. In each of these areas, diagnosis continues to rest on clinical findings and the judicious use of ancillary studies.

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          Author and article information

          Journal
          Mov Disord
          Movement disorders : official journal of the Movement Disorder Society
          Wiley
          0885-3185
          0885-3185
          May 2003
          : 18
          : 5
          Affiliations
          [1 ] Movement Disorder Program, University of Louisville, KY 40205, USA. i.litvan@louisville.edu
          Article
          10.1002/mds.10459
          12722160
          b34ce556-6d1d-4e40-b8f3-f6cbb34c8296
          Copyright 2003 Movement Disorder Society
          History

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