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      Brewer’s Yeast Improves Blood Pressure in Type 2 Diabetes Mellitus

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          Abstract

          Background

          This study was conducted to investigate the effects of Brewer’s yeast supplementation on serum lipoproteins and blood pressure in patients with Type 2 diabetes mellitus.

          Methods:

          In a randomized double blind clinical trial, 90 adults with type 2 diabetes mellitus were recruited, and divided randomly into 2 groups, trial group received brewer’s yeast (1800 mg/day) and control group received placebo for 12 weeks. Weight, BMI, food consumption (based on 24 hour food recall), fasting serum lipoproteins (Cholesterol, Triglyceride, LDL-c, HDL-c), systolic and diastolic blood pressures were measured before and after the intervention. Data analyses were performed by Statistical Package for Social Sciences ver. 18.0, and the statistical tests included Independent t-test, Paired t-test, Kolmogorov-Smirnov and analysis of covariance. This trial was registered in Iranian Registry of Clinical Trials (IRCT), No.IRCT138807062513N1.

          Results:

          Eighty-four subjects (21 men and 63 women) aged 46.3±6.1 years completed the study. After 12 weeks supplementation, systolic and diastolic blood pressures were decreased in the group receiving brewer’s yeast (4.1±1.5, P=0.007 and 5.7±0.6, P=0.001 respectively). No-significant changes in LDL-c, HDL-c, Triglyceride and Cholesterol were shown.

          Conclusion:

          Supplementation with Brewer’s yeast besides the usual treatment of type 2 diabetes mellitus can reduce systolic and diastolic blood pressures in diabetic patients.

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          Author and article information

          Journal
          Iran J Public Health
          Iran. J. Public Health
          IJPH
          Iranian Journal of Public Health
          Tehran University of Medical Sciences
          2251-6085
          2251-6093
          2013
          1 June 2013
          : 42
          : 6
          : 602-609
          Affiliations
          [1 ]International Campus, Tehran University of Medical Sciences, Tehran, Iran
          [2 ]Dept. of Nutrition and Biochemistry, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
          [3 ]Dept. of Biostatics and Epidemiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
          Author notes
          [* ]Corresponding Author: Tel: +98-21-88954911 Email: jalalimahmoud@ 123456hotmail.com
          Article
          ijph-42-602
          3744257
          23967428
          Copyright © Iranian Public Health Association & Tehran University of Medical Sciences

          This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0), which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.

          Categories
          Original Article

          Public health

          diabetes, brewer’s yeast, blood pressure

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