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      Safety of regular formoterol or salmeterol in children with asthma: an overview of Cochrane reviews.

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          Abstract

          Two large surveillance studies in adults with asthma have found an increased risk of asthma-related mortality in those who took regular salmeterol as monotherapy in comparison to placebo or regular salbutamol. No similar sized surveillance studies have been carried out in children with asthma, and we remain uncertain about the comparative safety of regular combination therapy with either formoterol or salmeterol in children with asthma.

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          Author and article information

          Journal
          Cochrane Database Syst Rev
          The Cochrane database of systematic reviews
          Wiley-Blackwell
          1469-493X
          1361-6137
          Oct 17 2012
          : 10
          Affiliations
          [1 ] Population Health Sciences and Education, St George’s, University of London, London, UK. ccates@sgul.ac.uk.
          Article
          EMS58498
          10.1002/14651858.CD010005.pub2
          4022036
          23076961
          b3ddb1eb-1d17-48c2-bdf1-bb2358fe06fe
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