18
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Hearing sensitivity in perinatally HIV-infected children

      abstract
      1 , , 1 , 1 , 1 , 1 , 1
      BMC Infectious Diseases
      BioMed Central
      International Symposium HIV and Emerging Infectious Diseases 2014
      21-23 May 2013

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Introduction Research on the effects of perinatal human immunodeficiency virus (HIV) exposure on hearing sensitivity is increasing. This is important because hearing loss can delay language and communication development in young children. The purpose of this project was to evaluate hearing sensitivity characteristics in HIV+ and HIV- children. Materials and methods Children were recruited from outpatient clinics within Tygerberg Children’s Hospital in Cape Town, South Africa. Caregiver report of middle ear infections was obtained through a questionnaire. Bilateral otoscopy, tympanometry, then pure-tone testing was completed. Hearing loss was defined as a pure-tone average (PTA) of 500, 1000, 2000, and 4000 Hz of >15 decibels of hearing level (dB HL) in the poorer ear. Unilateral hearing loss was defined as one normal ear and one ear with hearing loss. Conductive hearing loss was defined as an air-bone gap of ≥15 dB at a minimum of two frequencies in either ear. The percentage of children with hearing loss and mean PTA were compared between HIV+ and HIV- children. The effect of WHO status on hearing loss was examined for HIV+ children. Results Sixty-one children: 37 HIV+, 24 unexposed uninfected (HIV-), mean age 7.1 years (SD=1.6) were assessed. HIV+ children had a higher rate of reported middle ear infections and more conductive hearing loss. The risk for hearing loss was higher for HIV+ children (p=0.18), who also had a significantly higher mean PTA in the poorer ear than HIV- children (15.1 dB vs 8.6 dB, p=0.03). Six HIV+ children had unilateral hearing loss whereas one HIV- child had a unilateral hearing loss. Risk for hearing loss was higher for HIV+ children with WHO stage IV disease compared to other stages, but not significant. Conclusions There were more middle ear infections, a higher risk of hearing loss, and more unilateral hearing loss in HIV+ than HIV- children; HIV+ children had a significantly higher PTA (worse hearing) in their poorer ear. The risk of hearing loss was higher in those with WHO stage IV disease than those with stage II or III.

          Related collections

          Author and article information

          Conference
          BMC Infect Dis
          BMC Infect. Dis
          BMC Infectious Diseases
          BioMed Central
          1471-2334
          2014
          23 May 2014
          : 14
          : Suppl 2
          : P37
          Affiliations
          [1 ]San Diego State University, San Diego, USA
          Article
          1471-2334-14-S2-P37
          10.1186/1471-2334-14-S2-P37
          4220918
          b3e1deae-5ddb-4eeb-b2b8-9a6ec6138df9
          Copyright © 2014 Torre et al; licensee BioMed Central Ltd.

          This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

          International Symposium HIV and Emerging Infectious Diseases 2014
          Marseille, France
          21-23 May 2013
          History
          Categories
          Poster Presentation

          Infectious disease & Microbiology
          Infectious disease & Microbiology

          Comments

          Comment on this article