A prospective evaluation of whole brain volume loss and neurocognitive decline following hippocampal-sparing prophylactic cranial irradiation for limited-stage small-cell lung cancer.

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Abstract

This study evaluated an association between whole brain volume loss and neurocognitive decline following prophylactic cranial irradiation (PCI) for limited-stage small-cell lung cancer (SCLC).

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Author and article information

Journal

Journal ID (iso-abbrev): J Neurooncol

Title: Journal of neuro-oncology

Publisher: Springer Science and Business Media LLC

ISSN (Electronic): 1573-7373

ISSN (Print): 0167-594X

Publication date (Electronic): Sep 2019

Volume: 144

Issue: 2

Affiliations

[1 ] Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, 401 N. Broadway, Baltimore, MD, 21231, USA.

[2 ] Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, USA.

[3 ] Malone Center for Engineering in Healthcare, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA.

[4 ] Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA.

[5 ] Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, 401 N. Broadway, Baltimore, MD, 21231, USA. kjanson3@jhmi.edu.