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      A model for fast axonal transport.

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      Cell motility

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          Abstract

          A model for fast axonal transport is developed in which the essential features are that organelles may interact with mechanochemical cross-bridges that in turn interact with microtubules, forming an organelle-engine-microtubule complex which is transported along the microtubules. Computer analysis of the equations derived to describe such a system show that most of the experimental observations on fast axonal transport can be simulated by the model, indicating that the model is useful for the interpretation and design of experiments aimed at clarifying the mechanism of fast axonal transport.

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          Author and article information

          Journal
          Cell Motil.
          Cell motility
          0271-6585
          0271-6585
          1985
          : 5
          : 6
          Article
          2416456
          b4e71672-5601-4f19-a542-18cfc3aaa4a6
          History

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