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Cortical Surface-Based Analysis
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Abstract
Several properties of the cerebral cortex, including its columnar and laminar organization,
as well as the topographic organization of cortical areas, can only be properly understood
in the context of the intrinsic two-dimensional structure of the cortical surface.
In order to study such cortical properties in humans, it is necessary to obtain an
accurate and explicit representation of the cortical surface in individual subjects.
Here we describe a set of automated procedures for obtaining accurate reconstructions
of the cortical surface, which have been applied to data from more than 100 subjects,
requiring little or no manual intervention. Automated routines for unfolding and flattening
the cortical surface are described in a companion paper. These procedures allow for
the routine use of cortical surface-based analysis and visualization methods in functional
brain imaging.
Copyright 1999 Academic Press.