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Factors That Increase Risk of Celiac Disease Autoimmunity After a Gastrointestinal Infection in Early Life
Kaisa M. Kemppainen ,
Kristian F. Lynch ,
Edwin Liu ,
Maria Lönnrot ,
Ville Simell ,
Thomas Briese ,
Sibylle Koletzko ,
William Hagopian ,
Marian Rewers ,
Jin-Xiong She ,
Olli Simell ,
Jorma Toppari ,
Anette-G. Ziegler ,
Beena Akolkar ,
Jeffrey P. Krischer ,
Åke Lernmark ,
Heikki Hyöty ,
Eric W. Triplett ,
Daniel Agardh
May 2017
May 2017
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Abstract
Little is known about the pathogenic mechanisms of gluten immunogenicity in patients
with celiac disease. We studied temporal associations between infections and the development
of celiac disease autoimmunity, and examined effects of HLA alleles, rotavirus vaccination
status, and infant feeding.