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      Self-Reported Sleep Disturbance from Road, Rail and Aircraft Noise: Exposure-Response Relationships and Effect Modifiers in the SiRENE Study

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          Abstract

          This survey investigates the cross-sectional association between nighttime road, rail and aircraft noise exposure and the probability to be highly sleep disturbed (%HSD), as measured by self-report in postal and online questionnaires. As part of the Swiss SiRENE study, a total of 5592 survey participants in the entire country were selected based on a stratified random sample of their dwelling. Self-reported sleep disturbance was measured using an ICBEN-style 5-point verbal scale. The survey was carried out in four waves at different times of the year. Source-specific noise exposure was calculated for several façade points for each dwelling. After adjustment for potential confounders, all three noise sources showed a statistically significant association between the nighttime noise level LNight at the most exposed façade point and the probability to report high sleep disturbance, as determined by logistic regression. The association was strongest for aircraft noise and weakest for road traffic noise. We a priori studied the role of a range of effect modifiers, including the “eventfulness” of noise exposure, expressed as the Intermittency Ratio (IR) metric, bedroom window position, bedroom orientation towards the closest street, access to a quiet side of the dwelling, degree of urbanization, sleep timing factors (bedtime and sleep duration), sleep medication intake, survey season and night air temperature. While bedroom orientation exhibited a strong moderating effect, with an Leq-equivalent of nearly 20 dB if the bedroom faces away from the nearest street, the LNight-%HSD associations were not affected by bedroom window position, sleep timing factors, survey season, or temperature.

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          Most cited references39

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          Effect of nighttime aircraft noise exposure on endothelial function and stress hormone release in healthy adults

          Aims Aircraft noise disturbs sleep, and long-term exposure has been shown to be associated with increases in the prevalence of hypertension and an overall increased risk for myocardial infarction. The exact mechanisms responsible for these cardiovascular effects remain unclear. Methods and results We performed a blinded field study in 75 healthy volunteers (mean age 26 years), who were exposed at home, in random order, to one control pattern (no noise) and two different noise scenarios [30 or 60 aircraft noise events per night with an average maximum sound pressure level (SPL) of 60 dB(A)] for one night each. We performed polygraphy during each study night. Noise caused a worsening in sleep quality (P < 0.0001). Noise60, corresponding to equivalent continuous SPLs of 46.3 dB (Leq) and representing environmental noise levels associated with increased cardiovascular events, caused a blunting in FMD (P = 0.016). As well, although a direct comparison among the FMD values in the noise groups (control: 10.4 ± 3.8%; Noise30: 9.7 ± 4.1%; Noise60: 9.5 ± 4.3%, P = 0.052) did not reach significance, a monotone dose-dependent effect of noise level on FMD was shown (P = 0.020). Finally, there was a priming effect of noise, i.e. the blunting in FMD was particularly evident when subjects were exposed first to 30 and then to 60 noise events (P = 0.006). Noise-induced endothelial dysfunction (ED) was reversed by the administration of Vitamin C (P = 0.0171). Morning adrenaline concentration increased from 28.3 ± 10.9 to 33.2 ± 16.6 and 34.1 ± 19.3 ng/L (P = 0.0099). Pulse transit time, reflecting arterial stiffness, was also shorter after exposure to noise (P = 0.003). Conclusion In healthy adults, acute nighttime aircraft noise exposure dose-dependently impairs endothelial function and stimulates adrenaline release. Noise-induced ED may be in part due to increased production in reactive oxygen species and may thus be one mechanism contributing to the observed association of chronic noise exposure with cardiovascular disease.
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            STANDARDIZED GENERAL-PURPOSE NOISE REACTION QUESTIONS FOR COMMUNITY NOISE SURVEYS: RESEARCH AND A RECOMMENDATION

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              Road traffic noise effects on cardiovascular, respiratory, and metabolic health: An integrative model of biological mechanisms.

              Road traffic noise is a major public health issue, given the documented association with several diseases and the growing number of exposed persons all over the world. The effects widely investigated pertain to cardiovascular health, and to a lesser extent to respiratory and metabolic health. The epidemiological design of most studies has made it possible to ascertain long-term associations of urban noise with a number of cardiovascular, respiratory, and metabolic disorders and diseases; additionally, time series studies have reported short-term associations.

                Author and article information

                Journal
                Int J Environ Res Public Health
                Int J Environ Res Public Health
                ijerph
                International Journal of Environmental Research and Public Health
                MDPI
                1661-7827
                1660-4601
                29 October 2019
                November 2019
                : 16
                : 21
                : 4186
                Affiliations
                [1 ]Federal Office for the Environment, 3003 Bern, Switzerland
                [2 ]Empa, Swiss Federal Laboratories for Materials Science and Technology, 8600 Dübendorf, Switzerland; beat.schaeffer@ 123456empa.ch (B.S.); reto.pieren@ 123456empa.ch (R.P.);
                [3 ]Swiss Tropical and Public Health Institute, 4051 Basel, Switzerland; danielle.vienneau@ 123456swisstph.ch (D.V.); maria.foraster@ 123456isglobal.org (M.F.); ikenna.eze@ 123456swisstph.ch (I.C.E.); nicole.probst@ 123456swisstph.ch (N.P.-H.); martin.roosli@ 123456swisstph.ch (M.R.)
                [4 ]University of Basel, 4003 Basel, Switzerland
                [5 ]ISGlobal, Barcelona Institute for Global Health, 08003 Barcelona, Spain
                [6 ]University Pompeu Fabra, 08002 Barcelona, Spain
                [7 ]CIBER Epidemiologia y Salud Publica, 28029 Madrid, Spain
                [8 ]Blanquerna School of Health Science, Universitat Ramon Llull, 08022 Barcelona, Spain
                [9 ]Centre for Chronobiology, Psychiatric Hospital of the University of Basel, 4002 Basel, Switzerland; franziska.rudzik@ 123456posteo.de (F.R.); thiesse.laurie@ 123456gmail.com (L.T.); christian.cajochen@ 123456upk.ch (C.C.)
                [10 ]Transfaculty Research Platform Molecular and Cognitive Neurosciences, University of Basel, 4003 Basel, Switzerland
                Author notes
                Author information
                https://orcid.org/0000-0001-7661-4680
                https://orcid.org/0000-0002-1805-4117
                https://orcid.org/0000-0002-6309-6439
                https://orcid.org/0000-0001-5280-2230
                https://orcid.org/0000-0003-4450-4123
                https://orcid.org/0000-0001-9748-2162
                https://orcid.org/0000-0002-7475-1531
                Article
                ijerph-16-04186
                10.3390/ijerph16214186
                6861974
                31671890
                b5647d7a-3482-4b9d-a7ad-041462b4d1aa
                © 2019 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 28 August 2019
                : 25 October 2019
                Categories
                Article

                Public health
                noise exposure,sleep disturbance,exposure-effect relationship,traffic noise,noise effects,road traffic noise,railway noise,aircraft noise

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