Elena Marcos-Vadillo: Role: ConceptualizationRole: InvestigationRole: MethodologyRole: Writing – original
draft
Asunción García-Sánchez: Role: ConceptualizationRole: InvestigationRole: MethodologyRole: SupervisionRole:
Writing – review & editing
Catalina Sanz: Role: ConceptualizationRole: MethodologyRole: SupervisionRole: Writing – review &
editing
Ignacio Davila: Role: ConceptualizationRole: Funding acquisitionRole: SupervisionRole: Writing – review
& editing
María Isidoro-García: Role: ConceptualizationRole: MethodologyRole: SupervisionRole: Writing – review &
editing
Arun Rishi: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
31
October
2017
Publication date Collection: 2017
Volume: 12
Issue: 10
Electronic Location Identifier: e0186957
Affiliations
[1
]
Institute for Biomedical Research, IBSAL, Salamanca, Spain
[2
]
Department of Biomedical and Diagnostic Sciences, University of Salamanca, Salamanca,
Spain
[3
]
Department of Microbiology and Genetics, University of Salamanca, Salamanca, Spain
[4
]
Department of Allergy, University Hospital of Salamanca, Salamanca, Spain
[5
]
Department of Clinical Biochemistry, University Hospital of Salamanca, Salamanca,
Spain
[6
]
Department of Medicine, University of Salamanca, Salamanca, Spain
Wayne State University, UNITED STATES
Author notes
Competing Interests: The authors have declared that no competing interests exist.
Article
Publisher ID:
PONE-D-17-27191
DOI: 10.1371/journal.pone.0186957
PMC ID: 5663384
PubMed ID: 29088248
SO-VID: b566b377-d0b7-441e-9e91-7b16402b0500
Copyright © © 2017 Marcos-Vadillo et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: funder-id http://dx.doi.org/10.13039/501100004587, Instituto de Salud Carlos III;
Award ID: PI13/00564
Award Recipient
:
Ignacio Davila
Funded by: funder-id http://dx.doi.org/10.13039/501100004587, Instituto de Salud Carlos III;
Award ID: RD16/0006/0019
Award Recipient
:
Ignacio Davila
This work was supported by the Instituto de Salud Carlos III (grant PI13/00564 and
RETICS ARADyAL RD16/0006/0019) to ID. The funders had no role in study design, data
collection and analysis, decision to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Heredity
Subject:
Genetic Mapping
Subject:
Haplotypes
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Immune Physiology
Subject:
Cytokines
Subject:
Medicine and Health Sciences
Subject:
Physiology
Subject:
Immune Physiology
Subject:
Cytokines
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune System
Subject:
Innate Immune System
Subject:
Cytokines
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune System
Subject:
Innate Immune System
Subject:
Cytokines
Subject:
Biology and Life Sciences
Subject:
Developmental Biology
Subject:
Molecular Development
Subject:
Cytokines
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Gene Expression
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Enzymology
Subject:
Enzymes
Subject:
Oxidoreductases
Subject:
Luciferase
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Enzymes
Subject:
Oxidoreductases
Subject:
Luciferase
Subject:
Medicine and Health Sciences
Subject:
Pulmonology
Subject:
Asthma
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
DNA-binding proteins
Subject:
Transcription Factors
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Gene Expression
Subject:
Gene Regulation
Subject:
Transcription Factors
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Regulatory Proteins
Subject:
Transcription Factors
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Chemical Compounds
Subject:
Organic Compounds
Subject:
Alcohols
Subject:
Ethanol
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Organic Chemistry
Subject:
Organic Compounds
Subject:
Alcohols
Subject:
Ethanol
Subject:
Biology and life sciences
Subject:
Molecular biology
Subject:
Molecular biology techniques
Subject:
DNA construction
Subject:
Plasmid Construction
Subject:
Research and analysis methods
Subject:
Molecular biology techniques
Subject:
DNA construction
Subject:
Plasmid Construction