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      Similar amino acid sequences: chance or common ancestry?

      Science (New York, N.Y.)
      American Association for the Advancement of Science (AAAS)

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          Abstract

          The systemic comparison of every newly determined amino acid sequence with all other known sequences may allow a complete reconstruction of the evolutionary events leading to contemporary proteins. But sometimes the surviving similarities are so vague that even computer-based sequence comparisons procedures are unable to validate relationships. In other cases similar sequences may appear in totally alien proteins as a result of mere chance or, occasionally, by the convergent evolution of sequences with special properties.

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          Author and article information

          Journal
          Science
          Science (New York, N.Y.)
          American Association for the Advancement of Science (AAAS)
          0036-8075
          0036-8075
          Oct 09 1981
          : 214
          : 4517
          Article
          10.1126/science.7280687
          7280687
          b5890d3f-9667-4359-86f7-fa9615e869c0
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