Association of chemokine receptor 5 (CCR5) delta32 mutation with Behçet's disease is dependent on gender in Iranian patients.

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Abstract

Behçet's disease (BD) is a recurrent multi-system inflammatory disorder caused by the combinations of multiple genetic and environmental factors. CCR5 is a Th1-dominant chemokine receptor whose levels are increased in patients with active BD. It is believed that a 32 bp deletion in the CCR5 gene reduces the expression of this receptor on the cell surface. The aim of the present study was to investigate the association of CCR5 delta32 allele with BD in Iranian patients.

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Journal

Journal ID (iso-abbrev): Clin. Exp. Rheumatol.

Title: Clinical and experimental rheumatology

ISSN: 0392-856X

ISSN (Print): 0392-856X

Publication date (Electronic):

Volume: 24

Issue: 5 Suppl 42

Affiliations

[1 ] Shiraz Institute for Cancer Research, Shiraz University of Medical Sciences, Hafez Hospital, Shiraz, Iran.

Article

Publisher Item ID: 1892

PubMed ID: 17067435

SO-VID: b60d11ec-4949-407a-87fe-75d67c92f41e

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