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Possible low response of C-reactive protein production in eosinophilic pneumonia.

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      Abstract

      C-reactive protein (CRP) in the patients with eosinophilic pneumonia was examined compared with that of bacterial pneumonia. While no difference between erythrocyte sedimentation rate (ESR) in eosinophilic pneumonia (mean +/- SE: 74.5 +/- 10.6 mm/hr) and that in bacterial pneumonia (86.2 + 7.7 mm/hr) was observed, serum CRP level (3.87 +/- 1.24 mg/dL) and alpha 2-macroglobulin level (182.53 +/- 13.00 mg/dL) in eosinophilic pneumonia were lower in comparison with those in bacterial pneumonia (14.89 +/- 1.34 mg/dL, 315.65 +/- 11.54 mg/dL, respectively), suggesting that the pathogenesis of eosinophilic pneumonia might involve defective secretion of certain cytokine related to the production of acute-phase reactant proteins such as interleukin-6.

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      Affiliations
      [1 ] Department of Clinical and Laboratory Medicine, Akita University School of Medicine, Japan.
      Journal
      J Clin Lab Immunol
      Journal of clinical & laboratory immunology
      0141-2760
      0141-2760
      1995
      : 47
      : 1
      8735434

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