Studies show that 10 to 12 percent of the population in every culture worldwide is left-handed. Our main motivation was to seek general and specific knowledge of this lateral phenomena, left-handedness, mainly in terms of Psychology and Neuropsychology. We concentrated on lateral preference, function relations and investigation; their dependence on emotional lability, that is instability and possible dependency on personality characteristics. Chosen methods were strictly divided into two independent areas: lateral preferences and social characteristics of personality. For detection of lateral and preferential conditions the Test for Measuring Lateral Preferences and the Questionnaire of Social Perspectives were used. Neurotic symptoms were examined through Eysenck´s Questionnaire B-JEPI, and for the more complex view and incidence of neuroticism the computerized form of Bourdon´s Test was used, applied in the distraction conditions aimed at confirming, respectively the act of a disproving personality and social variables.