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Abstract
Ten non-pregnant heifers, experimentally infected with Leptospira interrogans serovar
hardjo, were each given an intramuscular injection of dihydrostreptomycin at a dose
rate of 25 mg kg-1. In five of these animals this treatment was repeated after 14
days. Treatment failed to remove established genital or renal infection in seven of
the 10 heifers, although the number of organisms persisting was apparently reduced
in these animals. Serovar hardjo infection persisted for at least 83 days in the oviduct
and uterus and these tissues may be as important carrier sites for serovar hardjo
as bovine kidney tissue.