23
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Athlete Atypicity on the Edge of Human Achievement: Performances Stagnate after the Last Peak, in 1988

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The growth law for the development of top athletes performances remains unknown in quantifiable sport events. Here we present a growth model for 41351 best performers from 70 track and field (T&F) and swimming events and detail their characteristics over the modern Olympic era. We show that 64% of T&F events no longer improved since 1993, while 47% of swimming events stagnated after 1990, prior to a second progression step starting in 2000. Since then, 100% of swimming events continued to progress.

          We also provide a measurement of the atypicity for the 3919 best performances (BP) of each year in every event. The secular evolution of this parameter for T&F reveals four peaks; the most recent (1988) followed by a major stagnation. This last peak may correspond to the most recent successful attempt to push forward human physiological limits. No atypicity trend is detected in swimming. The upcoming rarefaction of new records in sport may be delayed by technological innovations, themselves depending upon economical constraints.

          Related collections

          Most cited references14

          • Record: found
          • Abstract: found
          • Article: not found

          Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans.

          More than a billion humans worldwide are predicted to be completely deficient in the fast skeletal muscle fiber protein alpha-actinin-3 owing to homozygosity for a premature stop codon polymorphism, R577X, in the ACTN3 gene. The R577X polymorphism is associated with elite athlete status and human muscle performance, suggesting that alpha-actinin-3 deficiency influences the function of fast muscle fibers. Here we show that loss of alpha-actinin-3 expression in a knockout mouse model results in a shift in muscle metabolism toward the more efficient aerobic pathway and an increase in intrinsic endurance performance. In addition, we demonstrate that the genomic region surrounding the 577X null allele shows low levels of genetic variation and recombination in individuals of European and East Asian descent, consistent with strong, recent positive selection. We propose that the 577X allele has been positively selected in some human populations owing to its effect on skeletal muscle metabolism.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Similarity of polygenic profiles limits the potential for elite human physical performance.

            Human physical capability is influenced by many environmental and genetic factors, and it is generally accepted that physical capability phenotypes are highly polygenic. However, the ways in which relevant polymorphisms combine to influence the physical capability of individuals and populations are unknown. Initially, the literature was searched to identify associations between 23 genetic polymorphisms and human endurance phenotypes. Next, typical genotype frequencies of those polymorphisms in the general population were obtained from suitable literature. Using probability calculations, we found only a 0.0005% chance of a single individual in the world having the 'preferable' form of all 23 polymorphisms. As the number of DNA variants shown to be associated with human endurance phenotypes continues to increase, the probability of any single individual possessing the 'preferable' form of each polymorphism will become even lower. However, with population turnover, the chance of such genetically gifted individuals existing increases. To examine the polygenic endurance potential of a human population, a 'total genotype score' (for the 23 polymorphisms) was calculated for each individual within a hypothetical population of 1000 000. There was considerable homogeneity in terms of genetic predisposition to high endurance potential, with 99% of people differing by no more than seven genotypes from the typical profile. Consequently, with population turnover world and Olympic records should improve even without further enhancement of environmental factors, as more 'advantageous' polygenic profiles occasionally, though rarely, emerge. More broadly, human potential appears limited by the similarity of polygenic profiles at both the 'elite sport' and 'chronic disorder' ends of the performance continuum.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              The Citius End: World Records Progression Announces the Completion of a Brief Ultra-Physiological Quest

              World records (WR) in sports illustrate the ultimate expression of human integrated muscle biology, through speed or strength performances. Analysis and prediction of man's physiological boundaries in sports and impact of external (historical or environmental) conditions on WR occurrence are subject to scientific controversy. Based on the analysis of 3263 WR established for all quantifiable official contests since the first Olympic Games, we show here that WR progression rate follows a piecewise exponential decaying pattern with very high accuracy (mean adjusted r2 values = 0.91±0.08 (s.d.)). Starting at 75% of their estimated asymptotic values in 1896, WR have now reached 99%, and, present conditions prevailing, half of all WR will not be improved by more than 0,05% in 2027. Our model, which may be used to compare future athletic performances or assess the impact of international antidoping policies, forecasts that human species' physiological frontiers will be reached in one generation. This will have an impact on the future conditions of athlete training and on the organization of competitions. It may also alter the Olympic motto and spirit.
                Bookmark

                Author and article information

                Contributors
                Role: Editor
                Journal
                PLoS One
                plos
                plosone
                PLoS ONE
                Public Library of Science (San Francisco, USA )
                1932-6203
                2010
                20 January 2010
                : 5
                : 1
                : e8800
                Affiliations
                [1 ]IRMES, Insep, Paris, France
                [2 ]INSERM, U970, Paris, France
                [3 ]Paris Descartes University, Faculty of Sciences, Paris, France
                [4 ]Service d'hématologie Hôpital Necker and CNRS UMR 8147, Paris, France
                [5 ]Centre d'Investigation de la Médecine du Sport (CIMS), Hôtel-Dieu, Assistance Publique - Hôpitaux de Paris, Paris, France
                Pennington Biomedical Research Center, United States of America
                Author notes

                Conceived and designed the experiments: GB JFT. Performed the experiments: GB MT. Analyzed the data: GB MT NEH SE JT OH JFT. Contributed reagents/materials/analysis tools: GB MT SL SE MG HN JT VT FDD OH. Wrote the paper: GB JFT.

                Article
                09-PONE-RA-13760R1
                10.1371/journal.pone.0008800
                2808355
                20098706
                b7194176-08de-41f2-ac3a-a8b21e4f48a9
                Berthelot et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
                History
                : 23 October 2009
                : 4 January 2010
                Page count
                Pages: 8
                Categories
                Research Article
                Physiology
                Mathematics/Statistics
                Public Health and Epidemiology/Exercise and Sports
                Evolutionary Biology/Human Evolution

                Uncategorized
                Uncategorized

                Comments

                Comment on this article