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      Effect of phosphodiesterase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction: a randomized clinical trial.

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          Abstract

          Studies in experimental and human heart failure suggest that phosphodiesterase-5 inhibitors may enhance cardiovascular function and thus exercise capacity in heart failure with preserved ejection fraction (HFPEF).

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          Author and article information

          Journal
          JAMA
          JAMA
          American Medical Association (AMA)
          1538-3598
          0098-7484
          Mar 27 2013
          : 309
          : 12
          Affiliations
          [1 ] Department of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA. redfield.margaret@mayo.edu
          Article
          1663257 NIHMS498600
          10.1001/jama.2013.2024
          3835156
          23478662
          b719fd00-1e4a-4b6f-a406-fe9d82ebd584
          History

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