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      Variables associated with successful vascular access cannulation in hemodialysis patients: a prospective cohort study

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          Abstract

          Background

          Successful vascular access (VA) cannulation is integral to the delivery of adequate dialysis, highlighting the importance of ensuring the viability of arteriovenous access in hemodialysis (HD) patients. Missed VA cannulation can lead to infection, infiltration, hematoma or aneurysm formation resulting in the need for access revision, central venous catheter (CVC) placement, or permanent loss of VA. Cannulation-related complications can also negatively impact on a patient’s dialysis experience and quality of life. This study aimed to identify patient, VA and nurse factors associated with unsuccessful VA cannulations.

          Methods

          A prospective cohort study was conducted in HD patients with a permanent VA from three HD units. Data on patient, VA and nurse characteristics, plus, cannulation technique were collected for each episode of cannulation. General Estimating Equation was used to fit a repeated measures logistic regression to determine the odds of cannulation success.

          Results

          We collected data on 1946 episodes of cannulation (83.9% fistula) in 149 patients by 63 nurses. Cannulation included use of tourniquet (62.9%), ultrasound (4.1%) and was by rope ladder (73.8%) or area (24.7%) technique. The miscannulation rate was 4.4% ( n = 85) with a third of patients ( n = 47) having at least one episode of miscannulation. Extravasation ( n = 17, 0.9%) and use of an existing CVC ( n = 6, 0.6%) were rare. Multivariable characteristics of successful cannulation included fistula compared with graft [OR 4.38; 95%CI, 1.89–10.1]; older access [OR 1.68; 95%CI, 1.32–2.14]; absence of stent [OR 3.37; 95%CI, 1.39–8.19]; no ultrasound [OR 13.7; 95%CI, 6.52–28.6]; no tourniquet [OR 2.32; 95%CI, 1.15–4.66]; and lack of post graduate certificate in renal nursing [OR 2.27; 95%CI, 1.31–3.93].

          Conclusion

          This study demonstrated a low rate of miscannulation. Further research is required on ultrasound-guided cannulation. Identifying variables associated with successful cannulation may be used to develop a VA cannulation complexity instrument that could be utilised to match to the cannulation skill of a competency-assessed nurse, thereby minimising the risk of missed cannulation and trauma.

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          Most cited references23

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          2005 Annual Report: ESRD Clinical Performance Measures Project.

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            Cumulative patency of contemporary fistulas versus grafts (2000-2010).

            Comparisons of fistulas and grafts often overlook the high primary failure rate of fistulas. This study compared cumulative patency (time from access creation to permanent failure) of fistulas and grafts.
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              Complications of the Arteriovenous Fistula: A Systematic Review.

              The implementation of patient-centered care requires an individualized approach to hemodialysis vascular access, on the basis of each patient's unique balance of risks and benefits. This systematic review aimed to summarize current literature on fistula risks, including rates of complications, to assist with patient-centered decision making. We searched Medline from 2000 to 2014 for English-language studies with prospectively captured data on ≥100 fistulas. We assessed study quality and extracted data on study design, patient characteristics, and outcomes. After screening 2292 citations, 43 articles met our inclusion criteria (61 unique cohorts; n>11,374 fistulas). Median complication rates per 1000 patient days were as follows: 0.04 aneurysms (14 unique cohorts; n=1827 fistulas), 0.11 infections (16 cohorts; n>6439 fistulas), 0.05 steal events (15 cohorts; n>2543 fistulas), 0.24 thrombotic events (26 cohorts; n=4232 fistulas), and 0.03 venous hypertensive events (1 cohort; n=350 fistulas). Risk of bias was high in many studies and event rates were variable, thus we could not present pooled results. Studies generally did not report variables associated with fistula complications, patient comorbidities, vessel characteristics, surgeon experience, or nursing cannulation skill. Overall, we found marked variability in complication rates, partly due to poor quality studies, significant heterogeneity of study populations, and inconsistent definitions. There is an urgent need to standardize reporting of methods and definitions of vascular access complications in future clinical studies to better inform patient and provider decision making.
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                Author and article information

                Contributors
                l.coventry@ecu.edu.au
                jon.hosking@bbraun.com
                doris.chan@health.wa.gov.au
                evelyn.coral@health.wa.gov.au
                wai.lim@health.wa.gov.au
                a.towell-barnard@ecu.edu.au
                d.twigg@ecu.edu
                c.rickard@griffith.edu.au
                Journal
                BMC Nephrol
                BMC Nephrol
                BMC Nephrology
                BioMed Central (London )
                1471-2369
                31 May 2019
                31 May 2019
                2019
                : 20
                : 197
                Affiliations
                [1 ]ISNI 0000 0004 0437 5942, GRID grid.3521.5, Centre for Nursing Research, , Sir Charles Gairdner Hospital, ; Hospital Avenue, Nedlands, Western Australia 6009
                [2 ]ISNI 0000 0004 0389 4302, GRID grid.1038.a, School of Nursing & Midwifery, , Edith Cowan University, ; 270 Joondalup Drive, Joondalup, Western Australia 6027
                [3 ]Diaverum Toto Ora Dialysis Clinic, 10 Waddon Place, Mangere, New Zealand
                [4 ]ISNI 0000 0004 0437 5942, GRID grid.3521.5, Department of Renal Medicine, , Sir Charles Gairdner Hospital, ; Hospital Avenue, Nedlands, Western Australia 6009
                [5 ]ISNI 0000 0004 0437 5432, GRID grid.1022.1, Alliance for Vascular Access Teaching and Research, Menzies Health Institute Queensland and School of Nursing and Midwifery, , Griffith University, ; Nathan Campus, 170 Kessels Road, Nathan, Queensland 4111 Australia
                Author information
                http://orcid.org/0000-0002-3598-9942
                Article
                1373
                10.1186/s12882-019-1373-3
                6544962
                31151432
                b725fa72-c899-4ddb-9653-3091f82b1a5b
                © The Author(s). 2019

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 20 September 2018
                : 6 May 2019
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/501100001798, Edith Cowan University;
                Award ID: G1002171
                Award Recipient :
                Categories
                Research Article
                Custom metadata
                © The Author(s) 2019

                Nephrology
                arteriovenous fistulae,cannulation,cannulation-related complications,catheterization,hemodialysis,nursing,renal dialysis,vascular access

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