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      Neurological disorders of gait, balance and posture: a sign-based approach

      , , , , ,
      Nature Reviews Neurology
      Springer Nature

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          Abstract

          <p class="first" id="d440276e125">Neurological disorders of gait, balance and posture are both debilitating and common. Adequate recognition of these so-called disorders of axial mobility is important as they can offer useful clues to the underlying pathology in patients with an uncertain clinical diagnosis, such as those early in the course of neurological disorders. Medical teaching programmes typically take classic clinical presentations as the starting point and present students with a representative constellation of features that jointly characterize a particular axial motor syndrome. However, patients rarely present in this way to a physician in clinical practice. Particularly in the early stages of a disease, patients might display just one (or at best only a few) abnormal signs of gait, balance or posture. Importantly, these individual signs are never pathognomonic for any specific disorder but rather come with an associated differential diagnosis. In this Perspective, we offer a new diagnostic approach in which the presenting signs are taken as the starting point for a focused differential diagnosis and a tailored search into the underlying neurological syndrome. </p>

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          Author and article information

          Journal
          Nature Reviews Neurology
          Nat Rev Neurol
          Springer Nature
          1759-4758
          1759-4766
          January 29 2018
          January 29 2018
          :
          :
          Article
          10.1038/nrneurol.2017.178
          29377011
          b74059f4-75f7-4b2b-bb89-a23594049c1c
          © 2018
          History

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