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      "Masculinizing" effect on respiratory morbidity in girls from unlike-sex preterm twins: a possible transchorionic paracrine effect.

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          Abstract

          Preterm male infants are at a disadvantage when compared with female infants regarding the incidence of respiratory and neurologic morbidity and mortality. At term, female infants from unlike-sex twin pairs have birth weights that are closer to their male co-twins than to girls from like-sex twin pairs. We hypothesized that if the male disadvantage is mediated via factors that affect fetal lung development, there may be a potential effect on the incidence of respiratory distress syndrome and its complications in female infants from unlike-sex pairs.

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          Author and article information

          Journal
          Pediatrics
          Pediatrics
          American Academy of Pediatrics (AAP)
          1098-4275
          0031-4005
          Sep 2007
          : 120
          : 3
          Affiliations
          [1 ] Department of Neonatology, Kaplan Medical Center, PO Box 1, Rehovot 76100, Israel. eric_s@clalit.org.il
          120/3/e447
          10.1542/peds.2006-3574
          17766488

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