Objective The purpose of this study was to investigate the therapeutic effect of orthodontic treatment on anterior tooth displacement caused by periodontal disease. Methods A prospective study was performed in 86 patients with anterior tooth displacement caused by periodontal disease. These patients were divided into the experimental group and the control group according to the intervention methods. For the control group, patients were treated with conventional therapy. The experimental group used straight wire orthodontic technique for orthodontic treatment on the basis of conventional treatment. Comparisons were performed between two groups in term of bleeding index, alveolar bone height, anterior tooth coverage, periodontal pocket depth, probing depth, clinical crown length, tooth root length, inflammatory cytokines levels, and orthodontic satisfaction. Results Comparison of bleeding index, alveolar bone height, anterior tooth coverage, periodontal pocket depth, probing depth, clinical crown length, tooth root length, and inflammatory cytokines levels between two groups before treatment indicated that there were no statistical differences (all P > 0.05). After treatment, bleeding index, alveolar bone height, anterior tooth coverage, periodontal pocket depth, probing depth, clinical crown length, and serum levels of IL-6 and TNF-α in the experimental group were lower than those in the control group (all P < 0.05), while the serum level of IL-2 in the experimental group was more than that in the control group (P < 0.05). Also, there was no difference for tooth root length between two groups. Moreover, compared with the control group, orthodontic satisfaction in the experimental group was significantly increased. Conclusion The efficacy of orthodontic treatment in patients with anterior tooth displacement caused by periodontal disease is higher than that of only using conventional therapy, as it helps improve their periodontal health, alveolar bone height, clinical crown length, inflammatory factor levels, and orthodontic satisfaction of patients.
