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      Myopericarditis diagnosed by a 64-slice coronary CT angiography "triple rule out" protocol

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          Abstract

          We report a case of myopericarditis in a 30-year-old male complaining of shortness of breath. In an emergency department (ED) setting, the symptoms of myopericarditis may overlap with many disease entities and can be a challenging diagnosis to make. However, with the use of a 64-section coronary CT angiography in a “triple rule out” (TRO) protocol, we were able to detect a large pericardial effusion surrounding the heart and moderate global hypokinesis in the setting of normal-sized heart chambers and normal coronary arteries. We were further able to exclude pulmonary embolism and thoracic dissection. This is the first reported case of diagnosing myopericarditis using a TRO protocol. It demonstrates the usefulness of TRO in making an emergent diagnosis of myopericarditis while excluding other life-threatening diseases that can lead to earlier appropriate ED disposition and care.

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          Most cited references10

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          Myocarditis: current trends in diagnosis and treatment.

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            Noninvasive imaging in myocarditis.

            Increased recognition of the role of inflammation in acute and chronic dilated cardiomyopathy has revived an interest in noninvasive imaging for detection of myocarditis. Diagnostic strategies that are based on molecular imaging promise to further advance our understanding and improve diagnostic precision. This article reviews the strengths and limitations of common clinical tests used for the diagnosis of myocarditis, with a focus on the emerging role of cardiovascular magnetic resonance imaging. Novel imaging modalities that are currently in preclinical development are discussed with recommendations for future clinical research.
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              Viral myocarditis mimicking acute myocardial infarction.

              Anecdotal reports have shown that myocarditis can mimic acute myocardial infarction with chest pain, electrocardiographic (ECG) abnormalities, serum creatine kinase elevation and hemodynamic instability. Thirty-four patients with clinical signs and symptoms consistent with acute myocardial infarction underwent right ventricular endomyocardial biopsy during a 6.5-year period after angiographic identification of normal coronary anatomy. Myocarditis was found on histologic study in 11 of these 34 patients. Cardiogenic shock requiring intraaortic balloon support developed within 6 h of admission in three (27%) of the patients with myocarditis. The mean age of the group with myocarditis was 42 +/- 5 years. A preceding viral illness had been present in six patients (54%). The ECG abnormalities were varied and included ST segment elevation (n = 6), T wave inversions (n = 3), ST segment depression (n = 2) and pathologic Q waves (n = 2). The ECG abnormalities were typically seen in the anterior precordial leads but were diffusely evident in three patients. Left ventricular function was normal in six patients and globally decreased in the remaining five patients, whose ejection fraction ranged from 14% to 45%. Lymphocytic myocarditis was diagnosed in 10 patients, and giant cell myocarditis was detected in the remaining patient. Four patients with impaired left ventricular function received immunosuppressive therapy with prednisone and either azathioprine (n = 2) or cyclosporine (n = 2). All six patients whose left ventricular function was normal on admission remain alive in functional class I. Of the five patients with impaired systolic function, ejection fraction normalized in three of the four patients who received immunosuppressive therapy within 3 months of treatment and in the one patient who received only supportive therapy.(ABSTRACT TRUNCATED AT 250 WORDS)
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                Author and article information

                Contributors
                +1-215-9556844 , +1-215-9236225 , kevin.takakuwa@jefferson.edu
                Journal
                Int J Emerg Med
                International Journal of Emergency Medicine
                Springer-Verlag (London )
                1865-1372
                1865-1380
                21 August 2010
                21 August 2010
                December 2010
                : 3
                : 4
                : 447-449
                Affiliations
                [1 ]Department of Emergency Medicine, Thomas Jefferson University Hospital, 1020 Sansom Street, Suite 239 Thompson Building, Philadelphia, PA 19107 USA
                [2 ]Department of Radiology, Thomas Jefferson University Hospital, 111 South 11th St, Philadelphia, PA 19107 USA
                Article
                210
                10.1007/s12245-010-0210-z
                3047842
                21373320
                b8341bf7-a42b-4bb5-bda9-3a434ebed680
                © Springer-Verlag London Ltd 2010
                History
                : 6 April 2010
                : 15 June 2010
                Categories
                Case Report
                Custom metadata
                © Springer-Verlag London Ltd 2010

                Emergency medicine & Trauma
                myopericarditis,myocarditis,ct angiography,sixty-four section,pericarditis,triple rule-out

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