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      • Record: found
      • Abstract: found
      • Article: found

      Hemodynamic Changes after Ruthenium Irradiation of Hippel's Angiomatosis

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          Abstract

          The authors report a case of Hippel’s angiomatosis successfully treated with contact Β irradiation. The area of the multiplex retinal angioma and the accompanying retinal detachment was irradiated with a <sup>106</sup>Ru/<sup>106</sup>Rh radioactive applicator. Hemodynamic changes due to irradiation were followed up in the ipsilateral ophthalmic artery with transcranial Doppler sonography. Scarring was also demonstrated by fluorescein angiography and A- and B-scan ultrasonography. Irradiation caused the narrowing and later the occlusion of the precapillaries and capillaries (i.e. the resistance vessels) and that of the shunts inside the angioma; consequently, vascular resistance increased. Transcranial Doppler sonographic recordings showed a decrease in blood flow velocity as compared to pathologically increased blood flow velocity in angiomas, and a gradual increase in vascular resistance which was lower before treatment.

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          Author and article information

          Journal
          Journal ID (publisher-id): OPH
          Journal ID (nlm-ta): Ophthalmologica
          Journal ID (doi): 10.1159/issn.0030-3755
          Title: Ophthalmologica
          Publisher: S. Karger AG
          ISSN (Print): 0030-3755
          ISSN (Electronic): 1423-0267
          Publication date Subscription-year: 1990
          Publication date (Print): 1990
          Publication date (Electronic): 31 March 2010
          Volume: 200
          Issue: 3
          Pages: 128-132
          Affiliations
          aDepartments of Ophthalmology and bNeurosurgery, University Medical School of Debrecen, Hungary
          Article
          Publisher ID: 310093 Other ID: Ophthalmologica 1990;200:128–132
          DOI: 10.1159/000310093
          PubMed ID: 2189085
          SO-VID: b8710615-d9b3-4bc0-b49d-c722595067d4
          Copyright © © 1990 S. Karger AG, Basel
          License:

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Page count
          Pages: 5
          Categories
          Subject: Original Paper

          ScienceOpen disciplines: Vision sciences,Ophthalmology & Optometry,Pathology
          Keywords: Hippel’s angiomatosis,Hemodynamic changes in retinal angiomas,Transcranial Doppler sonography,Decreased vascular resistance,Increased blood flow velocity, I06Ru/106Rh application
          Data availability:
          ScienceOpen disciplines: Vision sciences, Ophthalmology & Optometry, Pathology
          Keywords: Hippel’s angiomatosis, Hemodynamic changes in retinal angiomas, Transcranial Doppler sonography, Decreased vascular resistance, Increased blood flow velocity, I06Ru/106Rh application

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