Journal ID (nlm-ta): PLoS Pathog
Journal ID (iso-abbrev): PLoS Pathog
Journal ID (publisher-id): plos
Journal ID (pmc): plospath
Title:
PLoS Pathogens
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1553-7366
ISSN
(Electronic):
1553-7374
Publication date
(Electronic):
3
August
2016
Publication date Collection:
August
2016
Volume: 12
Issue: 8
Electronic Location Identifier: e1005767
Affiliations
[1
]IAVI Neutralizing Center at TSRI, Department of Research and Development, International
AIDS Vaccine Initiative, La Jolla, California, United States of America
[2
]Department of Immunology and Microbial Science, The Scripps Research Institute, La
Jolla, California, United States of America
[3
]The Scripps CHAVI-ID, The Scripps Research Institute, La Jolla, California, United
States of America
[4
]Department of Integrative Structural and Computational Biology, The Scripps Research
Institute, La Jolla, California, United States of America
[5
]IAVI Design and Development Lab, Department of Research and Development, International
AIDS Vaccine Initiative, Brooklyn, New York, United States of America
University of Zurich, SWITZERLAND
Author notes
The authors have declared that no competing interests exist.
Conceived and designed the experiments: YF KT RTW. Performed the experiments: YF KT
NdV SB RW JG. Analyzed the data: YF KT NdV SB JG. Contributed reagents/materials/analysis
tools: SK HA JD ABW. Wrote the paper: YF KT RTW.
Author information
Article
Publisher ID:
PPATHOGENS-D-16-00497
DOI: 10.1371/journal.ppat.1005767
PMC ID: 4972253
PubMed ID: 27487086
SO-VID: b876f8ee-2d7e-4aa8-be79-8bff7364423f
Copyright © © 2016 Feng et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: HIVRAD
Award ID: AI104722
Award Recipient
:
Richard T. Wyatt
Funded by: CHAVI-ID
Award ID: AI100663
Award Recipient
:
Richard T. Wyatt
Funded by: CHAVI-ID
Award ID: AI100663
Award Recipient
:
Andrew B Ward
Funded by: funder-id http://dx.doi.org/10.13039/100000866, International AIDS Vaccine Initiative;
Award Recipient
:
Richard T. Wyatt
Funded by: funder-id http://dx.doi.org/10.13039/100000866, International AIDS Vaccine Initiative;
Award Recipient
:
Andrew B Ward
Funded by: funder-id http://dx.doi.org/10.13039/100000866, International AIDS Vaccine Initiative;
Award Recipient
:
ORCID: http://orcid.org/0000-0003-1564-4098
Yu Feng
Funded by: funder-id http://dx.doi.org/10.13039/100000866, International AIDS Vaccine Initiative;
Award Recipient
:
Karen Tran
Funded by: funder-id http://dx.doi.org/10.13039/100000866, International AIDS Vaccine Initiative;
Award Recipient
:
Javier Guenaga
Funded by: funder-id http://dx.doi.org/10.13039/100000866, International AIDS Vaccine Initiative;
Award Recipient
:
Heather Arendt
Funded by: funder-id http://dx.doi.org/10.13039/100000866, International AIDS Vaccine Initiative;
Award Recipient
:
Joanne DeStefano
Funded by: funder-id http://dx.doi.org/10.13039/100000866, International AIDS Vaccine Initiative;
Award Recipient
:
Shailendra Kumar
This work was funded by the HIVRAD grant number P01 AI104722 (RTW), CHAVI-ID grant
number AI100663 (ABW and RTW) and by the International AIDS Vaccine Initiative (IAVI)
and its generous donors (YF, KT, JG, SK, HA, JD, ABW and RTW). IAVI's work is made
possible by generous support from many donors including: the Bill & Melinda Gates
Foundation; the Ministry of Foreign Affairs of Denmark; Irish Aid; the Ministry of
Finance of Japan; the Ministry of Foreign Affairs of the Netherlands; the Norwegian
Agency for Development Cooperation (NORAD); the United Kingdom Department for International
Development (DFID), and the United States Agency for International Development (USAID).
The full list of IAVI donors is available at
www.iavi.org. This study is made possible by the generous support of the Bill & Melinda Gates
Foundation Collaboration for AIDS Vaccine Discovery and the American people through
USAID. The contents are the responsibility of the International AIDS Vaccine Initiative
and do not necessarily reflect the views of USAID or the United States Government.
The funders had no role in study design, data collection and analysis, decision to
publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Immune Physiology
Subject:
Antibodies
Subject:
Medicine and Health Sciences
Subject:
Physiology
Subject:
Immune Physiology
Subject:
Antibodies
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune System Proteins
Subject:
Antibodies
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune System Proteins
Subject:
Antibodies
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Immune System Proteins
Subject:
Antibodies
Subject:
Research and Analysis Methods
Subject:
Immunologic Techniques
Subject:
Immunoassays
Subject:
Enzyme-Linked Immunoassays
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Immune Physiology
Subject:
Antigens
Subject:
Medicine and Health Sciences
Subject:
Physiology
Subject:
Immune Physiology
Subject:
Antigens
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune System Proteins
Subject:
Antigens
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune System Proteins
Subject:
Antigens
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Immune System Proteins
Subject:
Antigens
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Physical Chemistry
Subject:
Chemical Bonding
Subject:
Cross-Linking
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Vaccination and Immunization
Subject:
Immunologic Adjuvants
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Vaccination and Immunization
Subject:
Immunologic Adjuvants
Subject:
Medicine and Health Sciences
Subject:
Public and Occupational Health
Subject:
Preventive Medicine
Subject:
Vaccination and Immunization
Subject:
Immunologic Adjuvants
Subject:
Research and Analysis Methods
Subject:
Electrophoretic Techniques
Subject:
Gel Electrophoresis
Subject:
Polyacrylamide Gel Electrophoresis
Subject:
Blue Native Polyacrylamide Gel Electrophoresis
Subject:
Research and Analysis Methods
Subject:
Model Organisms
Subject:
Animal Models
Subject:
Guinea Pigs
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Animals
Subject:
Vertebrates
Subject:
Amniotes
Subject:
Mammals
Subject:
Rodents
Subject:
Guinea Pigs
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Immune Cells
Subject:
Antibody-Producing Cells
Subject:
B Cells
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
Antibody-Producing Cells
Subject:
B Cells
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
Antibody-Producing Cells
Subject:
B Cells
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Blood Cells
Subject:
White Blood Cells
Subject:
B Cells
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
B Cells
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
B Cells
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
B Cells