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      Deployment of regulatory genes during gastrulation and germ layer specification in a model spiralian mollusc Crepidula.

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          Abstract

          During gastrulation, endoderm and mesoderm are specified from a bipotential precursor (endomesoderm) that is argued to be homologous across bilaterians. Spiralians also generate mesoderm from ectodermal precursors (ectomesoderm), which arises near the blastopore. While a conserved gene regulatory network controls specification of endomesoderm in deuterostomes and ecdysozoans, little is known about genes controlling specification or behavior of either source of spiralian mesoderm or the digestive tract.

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          Author and article information

          Journal
          Dev. Dyn.
          Developmental dynamics : an official publication of the American Association of Anatomists
          1097-0177
          1058-8388
          Oct 2015
          : 244
          : 10
          Affiliations
          [1 ] University of Illinois, Department of Cell and Developmental Biology, Urbana, Illinois.
          [2 ] Biology Department, Duke University, Durham, North Carolina.
          [3 ] Departamento de Biología Molecular and Centro de Biología Molecular, "Severo Ochoa" (CSIC, Universidad Autónoma de Madrid), Madrid, Spain.
          [4 ] Department of Metabolic Biochemistry, Ludwig-Maximilians-University, Munich, Germany.
          [5 ] Marine Biological Laboratory, Woods Hole, Massachusetts.
          [6 ] Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts.
          Article
          10.1002/dvdy.24308
          26197970
          b89f40b3-1445-4cb7-87ba-11bba347bbd8
          © 2015 Wiley Periodicals, Inc.
          History

          EMT,Mollusca,Spiralia,anus,blastopore,endoderm,foregut,gastrulation,hindgut,mesoderm,mouth

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