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Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study.
Abbas Dehghan
1 ,
Anna Köttgen ,
Qiong Yang ,
Shih-Jen Hwang ,
Wh Linda Kao ,
Fernando Rivadeneira ,
Eric Boerwinkle ,
Daniel Levy ,
Albert Hofman ,
Brad C Astor ,
Emelia J Benjamin ,
Cornelia M van Duijn ,
Jacqueline C Witteman ,
Josef Coresh ,
Caroline S Fox
Dec 06 2008
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Abstract
Hyperuricaemia, a highly heritable trait, is a key risk factor for gout. We aimed to identify novel genes associated with serum uric acid concentration and gout.